Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | RAB9A | P51151 | 2/20 | 0.69 |
| ▸ | GFER | P55789 | 1/20 | 0.69 |
| ▸ | ATP4A | P20648 | 17/20 | 0.61 |
| ▸ | ATP4B | P51164 | 17/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324082 | 0.89 | ATP4A (0.64) | MAPTNPC1RAB9AGFERATP4A | |
| SCHEMBL4334951 | 0.88 | ATP4A (0.58) | MAPTNPC1RAB9AGFERATP4A | |
| SCHEMBL4322753 | 0.86 | ATP4A (0.55) | MAPTNPC1RAB9AGFERATP4A | |
| SCHEMBL4322564 | 0.85 | ATP4A (0.54) | MAPTNPC1RAB9AGFERATP4A | |
| Bromide SCHEMBL826907 | 0.82 | MAPT (0.97) | MAPTNPC1RAB9AGFERATP4A | |
| SCHEMBL4330190 | 0.78 | KCNQ1 (0.53) | MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL4109611 | 0.77 | ATP4A (1.00) | MAPTNPC1RAB9AGFERATP4A | |
| SCHEMBL4338179 | 0.77 | ATP4A (0.61) | MAPTNPC1RAB9AGFERATP4A | |
| Bromide SCHEMBL826017 | 0.76 | ATP4A (1.00) | MAPTNPC1RAB9AGFERATP4A | |
| SCHEMBL4324285 | 0.75 | ATP4A (0.52) | MAPTNPC1RAB9AGFERATP4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |