Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATP4A | P20648 | 18/20 | 0.61 |
| ▸ | ATP4B | P51164 | 18/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334951 | 0.88 | ATP4A (0.58) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4334948 | 0.83 | ATP4A (0.57) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4338181 | 0.81 | MEN1 (0.48) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4324082 | 0.79 | ATP4A (0.64) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4322753 | 0.78 | ATP4A (0.55) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4330186 | 0.77 | MAPT (0.69) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4322564 | 0.71 | ATP4A (0.54) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL4330723 | 0.71 | PRSS1 (0.61) | ATP4AATP4BNPC1MAPTRAB9A | |
| Bromide SCHEMBL827268 | 0.69 | ATP4A (1.00) | ATP4AATP4BNPC1MAPTRAB9A | |
| SCHEMBL10672113 | 0.69 | ATP4A (0.74) | ATP4AATP4BNPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |