Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ1 | P51787 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4324085 | 0.89 | PHGDH (0.50) | MEN1KMT2AMAPTALDH1A1KDM4E | |
| SCHEMBL4334954 | 0.89 | MAPT (0.52) | KCNQ1MEN1KMT2ALMNAMAPT | |
| SCHEMBL4322757 | 0.87 | GSTO1 (0.51) | KCNQ1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL3603727 | 0.84 | GSTO1 (0.60) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL4330186 | 0.78 | MAPT (0.69) | MAPTNPC1RAB9ANPSR1 | |
| SCHEMBL3595657 | 0.78 | PTGS2 (0.66) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL4338181 | 0.77 | MEN1 (0.48) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL3601789 | 0.76 | KDM4E (0.60) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL4324290 | 0.76 | HSPA5 (0.52) | MEN1KMT2ALMNAMAPTKDM4E | |
| SCHEMBL10982710 | 0.75 | MAPT (0.45) | MEN1KMT2ALMNAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |