SCHEMBL4330787

SCHEMBL4330787

CC(C)(c1cc(Br)c(O)c(Br)c1)c1cc(Br)c(O)c(Br)c1.ClCC1CO1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.59
ALDH1A1 P00352 4/20 0.59
HIF1A Q16665 4/20 0.59
ALOX15 P16050 3/20 0.59
HSD17B10 Q99714 3/20 0.59
HPGD P15428 3/20 0.59
TDP1 Q9NUW8 3/20 0.59
ALOX12 P18054 2/20 0.59
CYP3A4 P08684 2/20 0.59
CASP1 P29466 1/20 0.59
RECQL P46063 1/20 0.59
CHEK1 O14757 1/20 0.47
DAPK3 O43293 1/20 0.47
RET P07949 1/20 0.47
PDGFRB P09619 1/20 0.47
PIM1 P11309 1/20 0.47
PDGFRA P16234 1/20 0.47
KDR P35968 1/20 0.47
MAPK8 P45983 1/20 0.47
RPS6KA3 P51812 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7574561 0.83 TSHR (0.58) TSHRALDH1A1HIF1AALOX15HSD17B10
SCHEMBL12643938 0.82 TSHR (0.53) TSHRALDH1A1HIF1AALOX15HSD17B10
SCHEMBL943782 0.82 TSHR (0.53) TSHRALDH1A1HIF1AALOX15HSD17B10
SCHEMBL18647 0.77 TSHR (1.00) TSHRALDH1A1HIF1AALOX15HSD17B10
SCHEMBL5173922 0.77 TSHR (1.00) TSHRALDH1A1HIF1AALOX15HSD17B10
Bisphenol A SCHEMBL442235 0.76 ESR1 (0.55) TSHRALDH1A1HIF1AHSD17B10HPGD
SCHEMBL16383381 0.74 TSHR (0.83) TSHRALDH1A1HIF1AALOX15HSD17B10
1,2-Dibromoethane SCHEMBL4910588 0.74 TSHR (0.83) TSHRALDH1A1HIF1AALOX15HSD17B10
SCHEMBL5953176 0.74 TSHR (0.83) TSHRALDH1A1HIF1AALOX15HSD17B10
SCHEMBL1104781 0.73 ALDH1A1 (0.55) TSHRALDH1A1HIF1AALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4347702-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2024-04-10 EP disclosed
EP-4153658-B1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2023-12-06 EP disclosed
US-20230272164-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2023-08-31 US disclosed
CN-116438244-A Crosslinkable organosiloxane modified reactive resins 瓦克化学股份公司 2023-07-14 CN disclosed
EP-4153658-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS Wacker Chemie AG (DE) 2023-03-29 EP disclosed
CN-115698139-A Crosslinkable organosiloxane-modified reaction resins 瓦克化学股份公司 2023-02-03 CN disclosed
WO-2022253413-A1 CROSS-LINKABLE ORGANOSILOXANE-MODIFIED REACTION RESINS WACKER CHEMIE AG (DE) 2022-12-08 WO disclosed
CN-105801524-B A kind of fluorination bisphenol type glycidol ether and its preparation method and application 武汉赫斯特涂层材料股份有限公司 2018-06-08 CN disclosed
CN-105801524-A Fluorination bisphenol-type glycidyl ether and preparing method and application thereof 武汉赫斯特涂层材料股份有限公司 2016-07-27 CN disclosed
WO-2009031146-A1 HIGH REFRACTIVE INDEX, LOW VISCOSITY ROOM TEMPERATURE TWO-PART EPOXY RESINS MEMPILE INC. (US) 2009-03-12 WO disclosed