Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12643938 | 0.87 | TSHR (0.53) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL943782 | 0.87 | TSHR (0.53) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL21097463 | 0.86 | ALDH1A1 (0.49) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL4330787 | 0.83 | TSHR (0.59) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL9053991 | 0.82 | TSHR (0.50) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL10696501 | 0.82 | ALDH1A1 (0.45) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL1104781 | 0.78 | ALDH1A1 (0.55) | TSHRALDH1A1HIF1AHPGDALOX15 | |
| SCHEMBL27924079 | 0.78 | SMN1; SMN2 (0.40) | TSHRALDH1A1HIF1AHSD17B10CYP3A4 | |
| SCHEMBL234097 | 0.77 | ALDH1A1 (0.36) | TSHRALDH1A1HIF1ACYP3A4TDP1 | |
| SCHEMBL16655607 | 0.76 | TSHR (0.61) | TSHRALDH1A1HIF1AHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5357027-A | Fireproof, heat resistant, impact resistant molding materials | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | claimed |
| US-20170137564-A1 | NOVEL INCLUSION COMPOUND | NIPPON SODA CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| EP-2980064-A1 | NOVEL INCLUSION COMPOUND | Nippon Soda Co., Ltd. (JP) | 2016-02-03 | — | — | EP | disclosed |
| US-20160017088-A1 | NOVEL INCLUSION COMPOUND | NIPPON SODA CO., LTD. (JP) | 2016-01-21 | — | — | US | disclosed |
| EP-0635528-B1 | Epoxy-modified polyamide resin | HITACHI CHEMICAL CO LTD (JP) | 2002-09-18 | — | — | EP | disclosed |
| US-5874518-A | Epoxy-modified polyamide resin | HITACHI CHEMICAL COMPANY, LTD. (JP) | 1999-02-23 | — | — | US | disclosed |
| US-5451632-A | Polycarbonate-polyorganosiloxane copolymer and a resin composition | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1995-09-19 | — | — | US | disclosed |
| EP-0635528-A2 | Epoxy-modified polyamide resin | Hitachi Chemical Co., Ltd. (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5357027-A | Fireproof, heat resistant, impact resistant molding materials | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1994-10-18 | — | — | US | disclosed |
| EP-0595141-A1 | A polycarbonate-polyorganosiloxane copolymer and a resin composition | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1994-05-04 | — | — | EP | disclosed |
| US-5185425-A | Flame retardance; impact resistance; thermostability at molding; appliances; construction materials | IDEMITSU PETROCHEMICAL CO., LTD. (JP) | 1993-02-09 | — | — | US | disclosed |
| US-3957905-A | HALOGENATED BISPHENYL COMPOUND, ANTIMONY COMPOUND | TOYO BOSEKI KABUSHIKI KAISHA (JA) | 1976-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160017088-A1 | NOVEL INCLUSION COMPOUND | SEM1, C9, EIF4A1 | TSHR 4677/4885ALDH1A1 440/4885HIF1A 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.