SCHEMBL4331088

SCHEMBL4331088

N=C(CCC(=O)OC(=O)c1cnccc1NN)OC(=O)c1cnccc1NN

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.37
MAPK9 P45984 1/20 0.37
MAPK10 P53779 1/20 0.37
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36
KDM4E B2RXH2 2/20 0.35
ALDH1A1 P00352 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
KDM4C Q9H3R0 4/20 0.33
SIRT3 Q9NTG7 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MPO P05164 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
CYP2D6 P10635 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL44217 0.96 MAPK8 (0.37) MAPK8MAPK9MAPK10CA12CA1
Acetone SCHEMBL16337583 0.95 MAPK8 (0.36) MAPK8MAPK9MAPK10CA12CA1
Hydrochloric Acid SCHEMBL14954478 0.74 ALDH1A1 (0.39) KDM4EALDH1A1TDP1
SCHEMBL6512756 0.74 ALDH1A1 (0.43) KDM4EALDH1A1GLAGAACYP1A2
Acetone SCHEMBL538074 0.73 ALDH1A1 (0.40) KDM4EALDH1A1TDP1
SCHEMBL6762577 0.72 ALDH1A1 (0.51) KDM4EALDH1A1GAASIRT3TDP1
Hydrazine SCHEMBL2725095 0.72 ALDH1A1 (0.48) KDM4EALDH1A1GAASIRT3TDP1
SCHEMBL4073078 0.72 TP53 (0.50) KDM4EALDH1A1GLAGAASIRT3
SCHEMBL4352598 0.71 KDM4E (0.55) MAPK10KDM4EALDH1A1GLAGAA
SCHEMBL5580002 0.71 NNMT (0.36) KDM4EGAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50754-E1 Compositions and method for multiplex biomarker profiling THE UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2026-01-20 US disclosed
US-RE50555-E1 Compositions and method for multiplex biomarker profiling UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2025-08-26 US disclosed
US-12332239-B2 Magnetic removal or identification of damaged or compromised cells or cellular structures INGURAN, LLC (US) 2025-06-17 US disclosed
US-20250109449-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION ROCHE SEQUENCING SOLUTIONS INC (US) 2025-04-03 US disclosed
US-20240254475-A1 PROTEOMIC ANALYSIS WITH NUCLEIC ACID IDENTIFIERS THE BROAD INSTITUTE, INC. 2024-08-01 US disclosed
WO-2022117731-A9 ELECTROSTATIC NANOPARTICLES AND USE THEREOF Westfälische Wilhelms-Universität Münster (DE) 2024-05-16 WO disclosed
US-20240091315-A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME AMUNIX PHARMACEUTICALS, INC. 2024-03-21 US disclosed
US-20240024500-A1 ELECTROSTATIC NANOPARTICLES AND USE THEREOF UNIVERSITÄT MÜNSTER (DE) 2024-01-25 US disclosed
US-11873483-B2 Proteomic analysis with nucleic acid identifiers THE BROAD INSTITUTE, INC. (US) 2024-01-16 US disclosed
US-20230384302-A1 MAGNETIC REMOVAL OR IDENTIFICATION OF DAMAGED OR COMPROMISED CELLS OR CELLULAR STRUCTURES INGURAN, LLC (US) 2023-11-30 US disclosed
US-11630108-B2 Cell processing using magnetic particles INGURAN, LLC (US) 2023-04-18 US disclosed
US-11549135-B2 Oligonucleotide-coupled antibodies for single cell or single complex protein measurements THE BROAD INSTITUTE, INC. (US) 2023-01-10 US disclosed
US-11531026-B2 Magnetic removal or identification of damaged or compromised cells or cellular structures INGURAN, LLC (US) 2022-12-20 US disclosed
US-RE49304-E1 Compositions and method for multiplex biomarker profiling UNIVERSITY OF WASHINGTON (US) 2022-11-22 US disclosed
EP-3551766-B1 INTEGRATED IMMUNO-PCR AND NUCLEIC ACID ANALYSIS IN AN AUTOMATED REACTION CARTRIDGE CEPHEID (US) 2022-09-14 EP disclosed
WO-2022117731-A1 ELECTROSTATIC NANOPARTICLES AND USE THEREOF Westfälische Wilhelms-Universität Münster (DE) 2022-06-09 WO disclosed
EP-4006550-A1 COMPOSITION FOR MAGNETIC REMOVAL OR IDENTIFICATION OF DAMAGED OR COMPROMISED CELLS OR CELLULAR STRUCTURES Inguran, LLC (US) 2022-06-01 EP disclosed
US-20220064741-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION Roche Sequencing Solutions, Inc. 2022-03-03 US disclosed
EP-3563933-B1 MAGNETIC REMOVAL OR IDENTIFICATION OF DAMAGED OR COMPROMISED CELLS OR CELLULAR STRUCTURES INGURAN LLC (US) 2022-03-02 EP disclosed
EP-2077113-A1 Treatment of autoimmune diseases Rheinische Friedrich-Wilhelms-Universität Bonn (DE) 2009-07-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250109449-A1 HIGH THROUGHPUT NUCLEIC ACID SEQUENCING BY EXPANSION ERCC4, NUDT21, XPNPEP1 MAPK8 2420/4885MAPK9 4282/4885MAPK10 4519/4885
US-20240024500-A1 ELECTROSTATIC NANOPARTICLES AND USE THEREOF FCGRT, NCL, EEA1 MAPK8 4395/4885MAPK9 2849/4885MAPK10 3720/4885
US-20240091315-A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME XPA, TXLNA, NGLY1 MAPK8 3072/4885MAPK9 4280/4885MAPK10 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.