Acetone

Acetone

SCHEMBL44217

CC(C)=O.N=C(CCC(=O)OC(=O)c1cnccc1NN)OC(=O)c1cnccc1NN

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK8 P45983 1/20 0.37
MAPK9 P45984 1/20 0.37
MAPK10 P53779 1/20 0.37
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
CA14 Q9ULX7 1/20 0.34
SIRT3 Q9NTG7 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KDM4C Q9H3R0 4/20 0.31
KDM6B O15054 2/20 0.31
LMNA P02545 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
TBK1 Q9UHD2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL16337583 0.99 MAPK8 (0.36) MAPK8MAPK9MAPK10KDM4EALDH1A1
SCHEMBL4331088 0.96 MAPK8 (0.37) MAPK8MAPK9MAPK10KDM4EALDH1A1
Acetone SCHEMBL538074 0.77 ALDH1A1 (0.40) KDM4EALDH1A1TDP1LMNAL3MBTL1
Acetone SCHEMBL1019108 0.73 NNMT (0.37) KDM4EGAATDP1LMNAL3MBTL1
Acetone SCHEMBL17732267 0.72 NNMT (0.36) KDM4EGAATDP1LMNAL3MBTL1
SCHEMBL4073078 0.72 TP53 (0.50) KDM4EALDH1A1GLAGAASIRT3
SCHEMBL6512756 0.72 ALDH1A1 (0.43) KDM4EALDH1A1GLAGAALMNA
Hydrochloric Acid SCHEMBL14954478 0.72 ALDH1A1 (0.39) KDM4EALDH1A1TDP1LMNAL3MBTL1
SCHEMBL4352598 0.71 KDM4E (0.55) MAPK10KDM4EALDH1A1GLAGAA
Acetone SCHEMBL5667714 0.71 SIRT3 (0.58) KDM4EALDH1A1GLAGAACA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 298 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10953073-B2 XTEN conjugate compositions and methods of making same AMUNIX PHARMACEUTICALS, INC. (US) 2021-03-23 US claimed
EP-2494075-B1 TEMPLATED NANOCONJUGATES UNIV NORTHWESTERN (US) 2018-04-04 EP claimed
EP-2494075-A2 TEMPLATED NANOCONJUGATES Northwestern University (US) 2012-09-05 EP claimed
EP-2341916-A1 COLOSTRUM COMPOSITION Nanoko A/S (DK) 2011-07-13 EP claimed
WO-2011053940-A2 TEMPLATED NANOCONJUGATES NORTHWESTERN UNIVERSITY (US) 2011-05-05 WO claimed
EP-2249661-A2 PRODUCTS AND METHODS TO PREVENT INFECTION Multimerics APS (DK) 2010-11-17 EP claimed
WO-2010028652-A1 COLOSTRUM COMPOSITION NANOKO A/S (DK) 2010-03-18 WO claimed
WO-2010021639-A1 ATTOMOLAR PROTEIN DETECTION IN COMPLEX DAMLE MATRICES WITH SEMI-HOMOGENEOUS FLUIDIC FORCE DISCRIMINATION ASSAYS THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2010-02-25 WO claimed
WO-2009092383-A2 PRODUCTS AND METHODS TO PREVENT INFECTION MULTIMERICS APS (DK) 2009-07-30 WO claimed
WO-2022117731-A9 ELECTROSTATIC NANOPARTICLES AND USE THEREOF Westfälische Wilhelms-Universität Münster (DE) 2024-05-16 WO disclosed
WO-2024092126-A1 COMPOSITIONS AND METHODS FOR IMPROVED IMMUNOTHERAPIES CARGO THERAPEUTICS, INC. (US) 2024-05-02 WO disclosed
US-20240091315-A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME AMUNIX PHARMACEUTICALS, INC. 2024-03-21 US disclosed
US-20240024500-A1 ELECTROSTATIC NANOPARTICLES AND USE THEREOF UNIVERSITÄT MÜNSTER (DE) 2024-01-25 US disclosed
US-11873483-B2 Proteomic analysis with nucleic acid identifiers THE BROAD INSTITUTE, INC. (US) 2024-01-16 US disclosed
EP-1351991-A2 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS Schwartz, David A. (US) 2003-10-15 EP disclosed
EP-1315699-A2 HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS Solulink, Incorporated (US) 2003-06-04 EP disclosed
US-20030013857-A1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents SOLULINK INCORPORATED 2003-01-16 US disclosed
US-20020146504-A1 Ternary biomolecule/polymer/surface-based immobilization systems AUDAX PRIVATE DEBT LLC, AS AGENT 2002-10-10 US disclosed
WO-2002057422-A2 TERNARY BIOMOLECULE/POLYMER/SURFACE-BASED IMMOBILIZATION SYSTEMS SCHWARTZ DAVID A (US) 2002-07-25 WO disclosed
WO-2001070685-A2 HYDRAZINE-BASED AND CARBONYL-BASED BIFUNCTIONAL CROSSLINKING REAGENTS SOLULINK, INCORPORATED (US) 2001-09-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020146504-A1 Ternary biomolecule/polymer/surface-based immobilization systems EPCAM, DNPEP, ANPEP MAPK8 3138/4885MAPK9 3810/4885MAPK10 3820/4885
US-10953073-B2 XTEN conjugate compositions and methods of making same XPA, TXLNA, NGLY1 MAPK8 3072/4885MAPK9 4280/4885MAPK10 2173/4885
US-20240024500-A1 ELECTROSTATIC NANOPARTICLES AND USE THEREOF FCGRT, NCL, EEA1 MAPK8 4395/4885MAPK9 2849/4885MAPK10 3720/4885
US-20030013857-A1 Hydrazine-based and carbonyl-based bifunctional crosslinking reagents HLCS, DUOX1, HAO2 MAPK8 3688/4885MAPK9 4007/4885MAPK10 4300/4885
US-20240091315-A1 XTEN CONJUGATE COMPOSITIONS AND METHODS OF MAKING SAME XPA, TXLNA, NGLY1 MAPK8 3072/4885MAPK9 4280/4885MAPK10 2173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.