Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 5/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP2 | P08253 | 3/20 | 0.49 |
| ▸ | MMP9 | P14780 | 3/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.49 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.49 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331282 | 1.00 | ADAMTS4 (0.49) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL6626990 | 0.82 | SLC1A3 (0.70) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL4330661 | 0.82 | SLC1A3 (0.70) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL4330656 | 0.82 | SLC1A3 (0.70) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL12890231 | 0.82 | KMT2A (0.50) | HPGDCYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL7335191 | 0.79 | MMP13 (0.52) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL7335195 | 0.79 | MMP13 (0.52) | ADAMTS4MMP13MMP2MMP9MMP3 | |
| SCHEMBL4619221 | 0.76 | MMP8 (0.51) | ADAMTS4MMP13MMP1MMP7SLC1A3 | |
| SCHEMBL7277829 | 0.76 | CYP2D6 (0.58) | CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL4621599 | 0.76 | MMP8 (0.51) | ADAMTS4MMP13MMP1MMP7SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7579487-B2 | Process for making N-sulfonated-amino acid derivatives | MERCK & CO., INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-20070219382-A1 | Process For Making N-Sulfonated-Amino Acid Derivatives | MERCK SHARP & DOHME CORP. | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219382-A1 | Process For Making N-Sulfonated-Amino Acid Derivatives | ANTXR2, STS, ASNS | ADAMTS4 3266/4885MMP13 3779/4885MMP2 2586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.