Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 3/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | FAP | Q12884 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433103 | 0.90 | HDAC2 (0.39) | HDAC2TACR3GSK3BMAPTKIT | |
| SCHEMBL432425 | 0.88 | HDAC2 (0.39) | HDAC2GSK3BMAPTKITPREP | |
| SCHEMBL434448 | 0.86 | HDAC2 (0.40) | HDAC2KITPREPFAPTAS1R3 | |
| SCHEMBL433153 | 0.86 | ANO1 (0.39) | TACR3GSK3BMAPTGSK3ATAS1R3 | |
| SCHEMBL431125 | 0.78 | SLC6A3 (0.45) | GSK3BMAPTGSK3ATAS1R3TAS1R1 | |
| SCHEMBL432998 | 0.77 | TAS1R3 (0.39) | HDAC2TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL433156 | 0.76 | MDM2 (0.42) | HDAC2KITPOLBHRH1SLC6A15 | |
| SCHEMBL432986 | 0.76 | MAPT (0.37) | TACR3GSK3BMAPTGSK3APOLB | |
| SCHEMBL432987 | 0.76 | MAPT (0.37) | TACR3GSK3BMAPTGSK3APOLB | |
| SCHEMBL432002 | 0.74 | TAS1R3 (0.38) | GSK3BGSK3ATAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |