Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.37 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.36 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.36 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.36 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.36 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.36 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.36 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.36 |
| ▸ | CACNG1 | Q06432 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433484 | 0.92 | HDAC1 (0.37) | TAS1R3TAS1R1TAS1R2PTGESANO1 | |
| SCHEMBL431263 | 0.92 | HDAC1 (0.37) | TAS1R3TAS1R1TAS1R2PTGESANO1 | |
| SCHEMBL432424 | 0.90 | PIK3CD (0.39) | TAS1R3TAS1R1TAS1R2ANO1PIK3CD | |
| SCHEMBL432998 | 0.88 | TAS1R3 (0.39) | TAS1R3TAS1R1TAS1R2ANO1PIK3CD | |
| SCHEMBL433153 | 0.88 | ANO1 (0.39) | TAS1R3TAS1R1TAS1R2ANO1TOP2A | |
| SCHEMBL432167 | 0.87 | TRPV1 (0.40) | TAS1R3TAS1R1TAS1R2PTGESANO1 | |
| SCHEMBL434762 | 0.80 | SLC6A3 (0.45) | TAS1R3TAS1R1TAS1R2GSK3AGSK3B | |
| SCHEMBL434448 | 0.79 | HDAC2 (0.40) | TAS1R3TAS1R1TAS1R2GPR119 | |
| SCHEMBL432425 | 0.76 | HDAC2 (0.39) | TAS1R3TAS1R1TAS1R2POLBGSK3B | |
| SCHEMBL432744 | 0.75 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012366-A1 | PESTICIDAL 3-(ARYLOXY)AZACYCLOALKANES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |