Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 5/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 4/20 | 0.39 |
| ▸ | PPARD | Q03181 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4335802 | 0.91 | SMN1; SMN2 (0.43) | PPARAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL4332405 | 0.91 | SMN1; SMN2 (0.43) | PPARAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL4328087 | 0.89 | KMT2A (0.44) | PPARAMMP1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4488496 | 0.89 | PPARA (0.41) | PPARAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL4336515 | 0.89 | LDHA (0.48) | ADRB2PPARAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4337170 | 0.88 | MMP1 (0.44) | PPARAMMP1MEN1KMT2AGAA | |
| SCHEMBL4340668 | 0.86 | OPRK1 (0.48) | PPARAMEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL6686370 | 0.86 | SMN1; SMN2 (0.43) | ADRB2MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL13810388 | 0.85 | ADRB2 (0.45) | ADRB2MEN1KMT2AL3MBTL1GAA | |
| SCHEMBL4341704 | 0.84 | GAA (0.49) | PPARAMMP1MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |
| US-7544835-B2 | Carboxylic acid derivative and salt thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-06-09 | — | — | US | disclosed |