Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578348 | 0.77 | PPARA (0.42) | PPARAPPARGACACBPPARDADRB3 | |
| SCHEMBL31407623 | 0.73 | PPARA (0.44) | PPARAPPARGALOX5PPARDADRB3 | |
| SCHEMBL4328328 | 0.72 | CALM1 (0.46) | ALDH1A1KDM4EADRB3 | |
| SCHEMBL2789562 | 0.72 | FFAR1 (0.59) | PPARA | |
| SCHEMBL3052267 | 0.72 | HRH3 (0.59) | PPARA | |
| SCHEMBL16789553 | 0.70 | ALOX5 (0.55) | ALOX5ALDH1A1LPAR1LPAR5 | |
| SCHEMBL23474931 | 0.69 | SLC6A4 (0.51) | PPARA | |
| SCHEMBL10389748 | 0.69 | ALDH1A1 (0.53) | PPARAPPARGACACBF2RL1ALDH1A1 | |
| SCHEMBL7502088 | 0.69 | CYP4F2 (0.56) | PPARAPPARGACACBALDH1A1SMN1; SMN2 | |
| SCHEMBL482856 | 0.69 | PPARA (0.51) | PPARAPPARGACACBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009147221-A1 | SMALL MOLECULE LEPTIN RECEPTOR MODULATORS | BIOVITRUM AB (PUBL) (SE) | 2009-12-10 | — | — | WO | disclosed |