SCHEMBL4333676

SCHEMBL4333676

O=S(=O)(c1cc(Cl)c(Cl)c(Cl)c1)c1cc(Cl)c(Cl)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 6/20 0.48
CA2 P00918 6/20 0.48
CA9 Q16790 6/20 0.48
CA12 O43570 2/20 0.48
CA4 P22748 2/20 0.48
CA6 P23280 2/20 0.48
CA5A P35218 2/20 0.48
CA7 P43166 2/20 0.48
CA14 Q9ULX7 2/20 0.48
CA5B Q9Y2D0 2/20 0.48
LMNA P02545 1/20 0.48
CYP2C9 P11712 1/20 0.48
CA13 Q8N1Q1 1/20 0.48
ALDH1A1 P00352 3/20 0.45
CYP3A4 P08684 3/20 0.43
MAPK1 P28482 1/20 0.43
HPGD P15428 2/20 0.41
HSD17B10 Q99714 2/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11795675 0.86 ALDH1A1 (0.70) CA1CA2CA9CA12CA4
SCHEMBL1036510 0.80 CA1 (0.46) CA1CA2CA9CA12CA4
SCHEMBL3139602 0.78 CA1 (0.45) CA1CA2CA9CA12CA4
SCHEMBL5981987 0.78 CA1 (0.70) CA1CA2CA9CA12CA4
SCHEMBL7993257 0.78 CA2 (0.75) CA1CA2CA9CA12CA4
SCHEMBL1347471 0.78 HSD17B10 (0.50) CA1CA2CA9CA12CYP2C9
SCHEMBL8459698 0.78 HSD17B10 (0.50) CA1CA2CA9CA12CYP2C9
SCHEMBL11857712 0.74 CA1 (0.42) CA1CA2CA9CA12CA4
SCHEMBL1958683 0.73 ALDH1A1 (0.52) ALDH1A1CYP3A4MAPK1HPGDHSD17B10
SCHEMBL16467678 0.72 CA1 (0.41) CA1CA2CA9CA12CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130245223-A1 HIGH HEAT POLYETHERSULFONE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-09-19 US disclosed
US-7635744-B2 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY (US) 2009-12-22 US disclosed
US-20070238856-A1 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY 2007-10-11 US disclosed
US-7273919-B1 High heat polyethersulfone compositions GENERAL ELECTRIC COMPANY (US) 2007-09-25 US disclosed
US-20070219344-A1 HIGH HEAT POLYETHERSULFONE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-09-20 US disclosed
US-20070117962-A1 High heat polyethersulfone compositions GENERAL ELECTRIC COMPANY (US) 2007-05-24 US disclosed