Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4341190 | 0.88 | OPRL1 (0.43) | OPRL1OPRM1ALDH1A1CHRM5CHRM3 | |
| SCHEMBL4341092 | 0.84 | OPRL1 (0.41) | OPRL1OPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL4330985 | 0.82 | SMN1; SMN2 (0.44) | OPRL1OPRM1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL4322729 | 0.81 | KCNA3 (0.40) | OPRL1OPRM1ALDH1A1OPRD1KCNH2 | |
| SCHEMBL4318217 | 0.75 | ADRA1D (0.40) | OPRL1OPRM1OPRD1OPRK1CA1 | |
| SCHEMBL4333175 | 0.75 | OPRM1 (0.43) | OPRL1OPRM1ALDH1A1MEN1KMT2A | |
| SCHEMBL4326114 | 0.75 | OPRM1 (0.43) | OPRL1OPRM1ALDH1A1MEN1KMT2A | |
| SCHEMBL4325746 | 0.75 | LMNA (0.48) | OPRL1OPRM1ALDH1A1MEN1KMT2A | |
| SCHEMBL4913158 | 0.73 | ALDH1A1 (0.67) | OPRL1OPRM1ALDH1A1CHRM5CHRM3 | |
| SCHEMBL4331690 | 0.73 | OPRM1 (0.43) | OPRL1OPRM1ALDH1A1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | ASTRAZENECA AB (SE) | 2009-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069340-A1 | Pyrazolone Compounds As Metabotropic Glutamate Receptor Agonists For The Treatment Of Neurological And Psychiatric Disorders | GRIN1, GRM1, GRIN3A | OPRL1 96/4885OPRM1 264/4885ALDH1A1 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.