Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4332805 | 0.87 | CA2 (0.52) | CA2NPSR1ATMCYP3A4GABRA1 | |
| SCHEMBL4343854 | 0.86 | GABRA1 (0.52) | ATMCYP3A4L3MBTL1GABRA1GABRB2 | |
| SCHEMBL4342474 | 0.80 | IAPP (0.41) | CYP3A4GABRA1GABRB2MAPTMEN1 | |
| SCHEMBL3165757 | 0.79 | CA2 (0.37) | CA2NPSR1ATMCYP3A4L3MBTL1 | |
| SCHEMBL4335272 | 0.78 | GABRA1 (0.54) | ATMCYP3A4L3MBTL1GABRA1GABRB2 | |
| SCHEMBL4342982 | 0.78 | GABRA1 (0.42) | CA2ATMCYP3A4L3MBTL1GABRA1 | |
| SCHEMBL6151612 | 0.78 | MEN1 (0.42) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL6150721 | 0.78 | PTGER4 (0.44) | MEN1HTTGFERKMT2AHSD17B10 | |
| SCHEMBL4332057 | 0.77 | IAPP (0.44) | GABRA1GABRB2 | |
| SCHEMBL3953857 | 0.76 | AKR1B1 (0.48) | CYP3A4TDP1MAPTMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3247734-B1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2022-08-31 | — | — | EP | disclosed |
| US-10370491-B2 | Preparation of highly heat-resistant (co)polycarbonates by the transesterification method | COVESTRO DEUTSCHLAND AG (DE) | 2019-08-06 | — | — | US | disclosed |
| US-20170369642-A1 | Preparation of Highly Heat-Resistant (Co)Polycarbonates by the Transesterification Method | COVESTRO DEUTSCHLAND AG (DE) | 2017-12-28 | — | — | US | disclosed |
| EP-3247734-A1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | Covestro Deutschland AG (DE) | 2017-11-29 | — | — | EP | disclosed |
| WO-2016116480-A1 | PREPARATION OF HIGHLY HEAT-RESISTANT (EO)POIYCARBONATES BY THE TRANSESTERIFICATION METHOD | COVESTRO DEUTSCHLAND AG (DE) | 2016-07-28 | — | — | WO | disclosed |
| US-20090117314-A1 | PROCESS FOR THE PREPARATION OF POLYCARBONATE BY THE MELT TRANSESTERIFICATION METHOD | BAYER MATERIALSCIENCE AG (DE) | 2009-05-07 | — | — | US | disclosed |