SCHEMBL6151612

SCHEMBL6151612

O=C(OCc1cccc(Cc2ccccc2)c1O)Oc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.42
HTT P42858 1/20 0.42
GFER P55789 1/20 0.42
KMT2A Q03164 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PTPN1 P18031 3/20 0.39
PTPN2 P17706 1/20 0.39
PTPN6 P29350 1/20 0.39
ELANE P08246 2/20 0.38
BCL2 P10415 1/20 0.38
BCL2L1 Q07817 1/20 0.38
CTSG P08311 1/20 0.37
ALOX5 P09917 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3980715 0.90 PTPN1 (0.44) PTPN1PTPN2PTPN6ELANEBCL2
SCHEMBL4343854 0.85 GABRA1 (0.52) MEN1HTTGFERKMT2AHSD17B10
SCHEMBL4342474 0.82 IAPP (0.41) MEN1HTTGFERKMT2AHSD17B10
SCHEMBL4335272 0.81 GABRA1 (0.54) MEN1HTTGFERKMT2AHSD17B10
SCHEMBL6150721 0.80 PTGER4 (0.44) MEN1HTTGFERKMT2AHSD17B10
SCHEMBL20097500 0.80 ALDH1A1 (0.52) KMT2A
SCHEMBL4332057 0.80 IAPP (0.44) BCL2L1ALOX5
SCHEMBL3953857 0.79 AKR1B1 (0.48) MEN1HTTGFERKMT2AHSD17B10
SCHEMBL4334985 0.78 CA2 (0.42) MEN1HTTGFERKMT2AHSD17B10
SCHEMBL4342982 0.78 GABRA1 (0.42) KMT2AELANEBCL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1427770-B1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GEN ELECTRIC (US) 2005-01-19 EP disclosed
EP-1427770-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2004-06-16 EP disclosed
US-20030120025-A1 Process for the production of polycarbonate GENERAL ELECTRIC COMPANY 2003-06-26 US disclosed
WO-2003022905-A1 PROCESS FOR THE PRODUCTION OF POLYCARBONATE GENERAL ELECTRIC COMPANY (US) 2003-03-20 WO disclosed
US-6525163-B1 Reducing static charge, improving heat aging, and lowering water absorption by increasing endcap levels GENERAL ELECTRIC COMPANY 2003-02-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030120025-A1 Process for the production of polycarbonate RNGTT, CAPG, RPL30 MEN1 3941/4885HTT 2326/4885GFER 2483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.