Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 13/20 | 0.69 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.69 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.69 |
| ▸ | MRGPRX2 | Q96LB1 | 3/20 | 0.62 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.62 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3476300 | 0.90 | OPRM1 (0.72) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL13998951 | 0.88 | OPRM1 (0.82) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL16922125 | 0.88 | OPRM1 (0.82) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL3476558 | 0.88 | OPRM1 (0.82) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| Aspirin SCHEMBL5482242 | 0.88 | OPRM1 (0.64) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL8418756 | 0.87 | OPRM1 (0.76) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| SCHEMBL8769434 | 0.87 | OPRM1 (0.67) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL16494311 | 0.86 | OPRD1 (0.79) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| Diacetylmorphine SCHEMBL2638139 | 0.86 | OPRD1 (0.79) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 | |
| Codeine SCHEMBL1642447 | 0.86 | OPRD1 (0.74) | OPRM1OPRK1OPRD1MRGPRX2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005086960-A2 | NARCOTIC-NSAID ION PAIRS | AAIPHARMA, INC. (US) | 2005-09-22 | — | — | WO | claimed |
| US-20050203115-A1 | Narcotic-NSAID ion pairs | WELLS FARGO BANK, N.A. | 2005-09-15 | — | — | US | claimed |
| WO-2017066488-A1 | TREATING PAIN USING A COMPOSITION COMPRISING AN OPIOID AND AN ANTIEMETIC | CHARLESTON LABORATORIES, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| EP-3129028-A1 | PHARMACEUTICAL COMPOSITIONS | Charleston Laboratories, Inc. (US) | 2017-02-15 | — | — | EP | disclosed |
| US-20150290211-A1 | PHARMACEUTICAL COMPOSITIONS | LOCL PHARMA, INC. | 2015-10-15 | — | — | US | disclosed |
| WO-2015157738-A1 | PHARMACEUTICAL COMPOSITIONS | CHARLESTON LABORATORIES, INC. (US) | 2015-10-15 | — | — | WO | disclosed |
| EP-2021502-A1 | NOVEL GENES AND MARKERS IN TYPE 2 DIABETES AND OBESITY | Oy Jurilab Ltd (FI) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007128884-A1 | NOVEL GENES AND MARKERS IN TYPE 2 DIABETES AND OBESITY | OY JURILAB LTD (FI) | 2007-11-15 | — | — | WO | disclosed |
| WO-2005086960-A2 | NARCOTIC-NSAID ION PAIRS | AAIPHARMA, INC. (US) | 2005-09-22 | — | — | WO | disclosed |
| US-20050203115-A1 | Narcotic-NSAID ion pairs | WELLS FARGO BANK, N.A. | 2005-09-15 | — | — | US | disclosed |
| US-5869498-A | ADMINISTERING A COMBINATION OF OXYCODONE, NAPROXEN AND A NONTOXIC N-METHYL-D-ASPARATATE (NMDA) RECEPTOR ANTAGONIST SUCH AS DEXTRORPHAN OR DEXTROMETHORPHAN | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1999-02-09 | — | — | US | disclosed |
| US-5863922-A | AN ANALGESICS MIXTURE COMPRISING ACETAMINOPHEN, SEDATIVE BUTALBITAL AND A N-METHYL-D-ASPARTATE RECEPTOR ANTAGONIST SELECTED FROM DEXTRORPHAN, DEXTROMETHORPHAN | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1999-01-26 | — | — | US | disclosed |
| US-5840731-A | COMPOSITION COMPRISING OPIOID ANALGESIC, ACETAMINOPHEN, NONTOXIC N-METHYL-D-ASPARTATE RECEPTOR ANTAGONIST | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0845989-A2 | PAIN-ALLEVIATING DRUG COMPOSITION AND METHOD FOR ALLEVIATING PAIN | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1998-06-10 | — | — | EP | disclosed |
| WO-1997004780-A2 | PAIN-ALLEVIATING DRUG COMPOSITION AND METHOD FOR ALLEVIATING PAIN | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1997-02-13 | — | — | WO | disclosed |