Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 6/20 | 0.41 |
| ▸ | TUBB | P07437 | 6/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 6/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 6/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 6/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 6/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 6/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 6/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 6/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 6/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 6/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 6/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 6/20 | 0.41 |
| ▸ | TUBB2B | Q9BVA1 | 6/20 | 0.41 |
| ▸ | TUBB1 | Q9H4B7 | 6/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4333037 | 0.76 | SLC6A9 (0.42) | SLC6A9ALDH1A1PTGS1HAO1MAPK13 | |
| SCHEMBL4335576 | 0.75 | SLC6A9 (0.47) | SLC6A9ALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL7807470 | 0.73 | HPGD (0.42) | ALDH1A1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL29062552 | 0.72 | SLC6A4 (0.42) | SLC6A9ALDH1A1ACHENFE2L2 | |
| SCHEMBL482240 | 0.70 | HAO1 (0.55) | NPC1RAB9AACHENFE2L2HAO1 | |
| SCHEMBL4705053 | 0.69 | NFE2L2 (0.51) | SLC6A9ALDH1A1SMN1; SMN2NFE2L2PTGS1 | |
| SCHEMBL4342646 | 0.69 | SLC6A9 (0.40) | SLC6A9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4347570 | 0.69 | PTGS1 (0.40) | SLC6A9TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3207761 | 0.68 | HSP90AA1 (0.43) | MAPK10NPC1RAB9ASMN1; SMN2NFE2L2 | |
| SCHEMBL1728265 | 0.67 | CA12 (0.46) | ALDH1A1MAPK10SMN1; SMN2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612068-B2 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2009-11-03 | — | — | US | disclosed |
| US-20060235003-A1 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2006-10-19 | — | — | US | disclosed |
| EP-1622868-A1 | AROMATIC OXYPHENYL AND AROMATIC SULFANYLPHENYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2006-02-08 | — | — | EP | disclosed |
| WO-2004096761-A1 | AROMATIC OXYPHENYL AND AROMATIC SULFANYLPHENYL DERIVATIVES | H. LUNDBECK A/S (DK) | 2004-11-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235003-A1 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | TYR, TPST2, COMT | SLC6A9 2305/4885ALDH1A1 425/4885TUBB4A 1030/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.