SCHEMBL4335957

SCHEMBL4335957

CCOC(OCC)[SiH2]CN(C)C1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
HRH4 Q9H3N8 1/20 0.34
HRH3 Q9Y5N1 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
ALDH1A1 P00352 1/20 0.31
ADH1C P00326 1/20 0.31
ADH1A P07327 1/20 0.31
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4333773 0.84 ADH1A (0.32) ADH1CADH1A
SCHEMBL1775545 0.73 KMT2A (0.42) HRH4HRH3MEN1KMT2AALDH1A1
SCHEMBL379571 0.71 THRB (0.35)
SCHEMBL17750056 0.71 CYP1A2 (0.34)
SCHEMBL3889901 0.70 SHBG (0.33)
SCHEMBL11775946 0.68 ADH1A (0.35) HRH4HRH3MEN1KMT2AALDH1A1
SCHEMBL28155611 0.67 THRB (0.32)
SCHEMBL467904 0.67 KDM4E (0.37) MEN1KMT2AALDH1A1KDM4E
SCHEMBL170201 0.66 ADH1A (0.48) HRH4HRH3ALDH1A1ADH1CADH1A
SCHEMBL21180049 0.66 ADH1A (0.48) HRH4HRH3ALDH1A1ADH1CADH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220142905-A1 COSMETIC PRODUCT CONTAINING A MIXTURE OF SILICONES HENKEL AG & CO. KGAA (DE) 2022-05-12 US disclosed
US-11213476-B2 Method for gentle, chemical hair treatment HENKEL AG & CO. KGAA (DE) 2022-01-04 US disclosed
US-20200138694-A1 METHOD FOR GENTLE, CHEMICAL HAIR TREATMENT HENKEL AG & CO. KGAA (DE) 2020-05-07 US disclosed
US-8304023-B2 coating with a condensation-curable organopolysiloxanes with silanes to form elastomeric films insoluble in toluene; formed layer has a permanent soft hand and good bulk, no yellowing, free of volatile organic compounds; storage stability, solvent-free WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
EP-1721926-B1 Process for the production of dispersions of cross linked organopolysiloxanes WACKER CHEMIE AG (DE) 2009-07-01 EP disclosed
US-20080107814-A1 Treatment Of Fiberfill Fibers With Aqueous Dispersions Of Organopolysiloxanes WACKER CHEMIE AG (DE) 2008-05-08 US disclosed
US-20080064813-A1 METHOD FOR PRODUCING CROSSLINKABLE ORGANOPOLYSILOXANE DISPERSIONS WACKER CHEMIE AG (DE) 2008-03-13 US disclosed
EP-1721926-A1 Process for the production of dispersions of cross linked organopolysiloxanes Wacker Chemie AG (DE) 2006-11-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200138694-A1 METHOD FOR GENTLE, CHEMICAL HAIR TREATMENT KRT18, POLR1C, TUBA1C HRH4 2255/4885HRH3 2363/4885MEN1 3803/4885
US-11213476-B2 Method for gentle, chemical hair treatment KRT18, POLR1C, TUBA1C HRH4 2255/4885HRH3 2363/4885MEN1 3803/4885
US-20220142905-A1 COSMETIC PRODUCT CONTAINING A MIXTURE OF SILICONES SQLE, LIPA, HSD17B4 HRH4 2251/4885HRH3 1286/4885MEN1 1005/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.