Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4336062 | 0.81 | HCAR2 (0.31) | ELANE | |
| SCHEMBL299791 | 0.80 | HPGD (0.42) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL2028631 | 0.77 | THRB (0.50) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL27082345 | 0.70 | HPGD (0.43) | TDP1 | |
| SCHEMBL26936566 | 0.68 | HPGD (0.41) | POLBAPEX1HTTTDP1ELANE | |
| SCHEMBL18061412 | 0.68 | CHRM1 (0.58) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL18770237 | 0.68 | THRB (0.41) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL24634077 | 0.68 | THRB (0.49) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL7778106 | 0.68 | HPGD (0.37) | THRBELANE | |
| SCHEMBL235139 | 0.68 | MTNR1A (0.49) | POLBAPEX1HTTTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1928979-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-03-04 | — | — | EP | disclosed |