Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL435356 | 0.88 | NOX1 (0.35) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL434444 | 0.86 | NOX1 (0.36) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL563959 | 0.86 | GAA (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL432486 | 0.85 | MEN1 (0.45) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL433232 | 0.84 | NOX1 (0.42) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL434466 | 0.83 | MAPT (0.46) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL10370002 | 0.82 | GAA (0.48) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL433397 | 0.81 | MAPT (0.41) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL434961 | 0.81 | NOX1 (0.46) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL436033 | 0.80 | NOX1 (0.41) | MAPTGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | claimed |
| EP-1867732-A1 | Reagents, methods and devices for detecting analytes | Bayer Corporation (US) | 2007-12-19 | — | — | EP | claimed |
| EP-1293574-B1 | Reagents, methods and devices for detecting analytes | BAYER CORP (US) | 2007-11-21 | — | — | EP | claimed |
| US-7163616-B2 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | BAYER CORPORATION (US) | 2007-01-16 | — | — | US | claimed |
| US-20030094384-A1 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2003-05-22 | — | — | US | claimed |
| EP-1293574-A2 | Reagents, methods and devices for detecting analytes | Bayer Corporation (US) | 2003-03-19 | — | — | EP | claimed |
| EP-0747984-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2002-08-14 | — | — | EP | claimed |
| EP-0747984-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-12-11 | — | — | EP | claimed |
| US-5520786-A | ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES | BAYER CORPORATION (US) | 1996-05-28 | — | — | US | claimed |
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| US-20220275348-A1 | ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS | ROCHE DIABETES CARE, INC. | 2022-09-01 | — | — | US | disclosed |
| US-11180790-B2 | Reagents and methods for detecting analytes | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2021-11-23 | — | — | US | disclosed |
| EP-3388824-B1 | METHODS OF DETECTING HIGH ANTIOXIDANT LEVELS DURING ELECTROCHEMICAL MEASUREMENTS AND FAILSAFING AN ANALYTE CONCENTRATION THEREFROM AS WELL AS DEVICES AND SYSTEMS INCORPORTING THE SAME | ROCHE DIABETES CARE GMBH (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20200270668-A1 | REAGENTS AND METHODS FOR DETECTING ANALYTES | BAYER HEALTHCARE, LLC | 2020-08-27 | — | — | US | disclosed |
| US-7163616-B2 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | BAYER CORPORATION (US) | 2007-01-16 | — | — | US | disclosed |
| US-20030094384-A1 | Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes | ASCENSIA DIABETES CARE HOLDINGS AG (CH) | 2003-05-22 | — | — | US | disclosed |
| EP-1293574-A2 | Reagents, methods and devices for detecting analytes | Bayer Corporation (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-0747984-B1 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | BAYER AG (US) | 2002-08-14 | — | — | EP | disclosed |
| EP-0747984-A2 | Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof | Bayer Corporation (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5520786-A | ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES | BAYER CORPORATION (US) | 1996-05-28 | — | — | US | disclosed |