SCHEMBL434466

SCHEMBL434466

COc1ccc(N=C2C=CC3=C(C2)Sc2ccccc2N3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 9/20 0.46
▸ MEN1 O00255 7/20 0.46
▸ KMT2A Q03164 7/20 0.46
▸ GAA P10253 4/20 0.46
▸ SMN1; SMN2 Q16637 4/20 0.46
▸ NOX1 Q9Y5S8 3/20 0.46
▸ TDP1 Q9NUW8 3/20 0.46
▸ MAPK1 P28482 3/20 0.46
▸ HTT P42858 2/20 0.46
▸ LMNA P02545 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ ALDH1A1 P00352 5/20 0.41
▸ TTR P02766 1/20 0.41
▸ LRRK2 Q5S007 1/20 0.41
▸ NPC1 O15118 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ SNCA P37840 2/20 0.35
▸ KDM4E B2RXH2 2/20 0.35
▸ POLB P06746 2/20 0.35
▸ APEX1 P27695 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL563959 0.86 GAA (0.42) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL433232 0.84 NOX1 (0.42) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL433635 0.83 MAPT (0.39) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL433397 0.83 MAPT (0.41) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL10371400 0.83 NOX1 (0.47) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL434961 0.81 NOX1 (0.46) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL435356 0.81 NOX1 (0.35) MAPTMEN1KMT2AGAANOX1
SCHEMBL432486 0.80 MEN1 (0.45) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL436033 0.80 NOX1 (0.41) MAPTMEN1KMT2AGAASMN1; SMN2
SCHEMBL434444 0.79 NOX1 (0.36) MAPTMEN1KMT2AGAASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851685-B2 Zwitterion buffer containing compositions and uses in electroanalytical devices and methods ROCHE DIABETES CARE, INC. (US) 2023-12-26 — — US claimed
EP-1867732-A1 Reagents, methods and devices for detecting analytes Bayer Corporation (US) 2007-12-19 — — EP claimed
EP-1293574-B1 Reagents, methods and devices for detecting analytes BAYER CORP (US) 2007-11-21 — — EP claimed
US-7163616-B2 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes BAYER CORPORATION (US) 2007-01-16 — — US claimed
US-20030094384-A1 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2003-05-22 — — US claimed
EP-1293574-A2 Reagents, methods and devices for detecting analytes Bayer Corporation (US) 2003-03-19 — — EP claimed
EP-0747984-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2002-08-14 — — EP claimed
EP-0747984-A2 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1996-12-11 — — EP claimed
US-5520786-A ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES BAYER CORPORATION (US) 1996-05-28 — — US claimed
US-11851685-B2 Zwitterion buffer containing compositions and uses in electroanalytical devices and methods ROCHE DIABETES CARE, INC. (US) 2023-12-26 — — US disclosed
US-20220275348-A1 ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS ROCHE DIABETES CARE, INC. 2022-09-01 — — US disclosed
US-11180790-B2 Reagents and methods for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-11-23 — — US disclosed
EP-3388824-B1 METHODS OF DETECTING HIGH ANTIOXIDANT LEVELS DURING ELECTROCHEMICAL MEASUREMENTS AND FAILSAFING AN ANALYTE CONCENTRATION THEREFROM AS WELL AS DEVICES AND SYSTEMS INCORPORTING THE SAME ROCHE DIABETES CARE GMBH (DE) 2021-04-14 — — EP disclosed
US-20200270668-A1 REAGENTS AND METHODS FOR DETECTING ANALYTES BAYER HEALTHCARE, LLC 2020-08-27 — — US disclosed
US-7163616-B2 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes BAYER CORPORATION (US) 2007-01-16 — — US disclosed
US-20030094384-A1 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2003-05-22 — — US disclosed
EP-1293574-A2 Reagents, methods and devices for detecting analytes Bayer Corporation (US) 2003-03-19 — — EP disclosed
EP-0747984-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2002-08-14 — — EP disclosed
EP-0747984-A2 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1996-12-11 — — EP disclosed
US-5520786-A ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES BAYER CORPORATION (US) 1996-05-28 — — US disclosed
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