SCHEMBL434444

SCHEMBL434444

NCCc1ccc(N=C2C=CC3=C(C2)Sc2ccccc2N3)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NOX1 Q9Y5S8 4/20 0.36
▸ GAA P10253 3/20 0.36
▸ MAPT P10636 3/20 0.36
▸ BCHE P06276 2/20 0.36
▸ ACHE P22303 2/20 0.36
▸ MEN1 O00255 1/20 0.36
▸ CYP1A2 P05177 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ ADORA3 P0DMS8 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ ALOX12 P18054 1/20 0.36
▸ MAOA P21397 1/20 0.36
▸ CNR1 P21554 1/20 0.36
▸ PTGS1 P23219 1/20 0.36
▸ SLC6A2 P23975 1/20 0.36
▸ HTR2C P28335 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ SNCA P37840 1/20 0.36
▸ SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL435356 0.91 NOX1 (0.35) NOX1GAAMAPTBCHEACHE
SCHEMBL433635 0.86 MAPT (0.39) NOX1GAAMAPTBCHEACHE
SCHEMBL563959 0.84 GAA (0.42) NOX1GAAMAPTBCHEACHE
SCHEMBL433232 0.82 NOX1 (0.42) NOX1GAAMAPTBCHEACHE
SCHEMBL434961 0.79 NOX1 (0.46) NOX1GAAMAPTBCHEACHE
SCHEMBL434466 0.79 MAPT (0.46) NOX1GAAMAPTBCHEACHE
SCHEMBL432486 0.78 MEN1 (0.45) NOX1GAAMAPTBCHEACHE
SCHEMBL436033 0.78 NOX1 (0.41) NOX1GAAMAPTBCHEACHE
SCHEMBL434952 0.77 SNCA (0.48) NOX1GAAMAPTBCHEACHE
SCHEMBL433397 0.74 MAPT (0.41) NOX1GAAMAPTMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11851685-B2 Zwitterion buffer containing compositions and uses in electroanalytical devices and methods ROCHE DIABETES CARE, INC. (US) 2023-12-26 — — US claimed
EP-1293574-B1 Reagents, methods and devices for detecting analytes BAYER CORP (US) 2007-11-21 — — EP claimed
US-7163616-B2 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes BAYER CORPORATION (US) 2007-01-16 — — US claimed
US-20030094384-A1 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2003-05-22 — — US claimed
EP-1293574-A2 Reagents, methods and devices for detecting analytes Bayer Corporation (US) 2003-03-19 — — EP claimed
EP-0747984-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2002-08-14 — — EP claimed
EP-0747984-A2 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1996-12-11 — — EP claimed
US-5520786-A ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES BAYER CORPORATION (US) 1996-05-28 — — US claimed
US-11851685-B2 Zwitterion buffer containing compositions and uses in electroanalytical devices and methods ROCHE DIABETES CARE, INC. (US) 2023-12-26 — — US disclosed
US-20220275348-A1 ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS ROCHE DIABETES CARE, INC. 2022-09-01 — — US disclosed
US-11180790-B2 Reagents and methods for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2021-11-23 — — US disclosed
EP-3388824-B1 METHODS OF DETECTING HIGH ANTIOXIDANT LEVELS DURING ELECTROCHEMICAL MEASUREMENTS AND FAILSAFING AN ANALYTE CONCENTRATION THEREFROM AS WELL AS DEVICES AND SYSTEMS INCORPORTING THE SAME ROCHE DIABETES CARE GMBH (DE) 2021-04-14 — — EP disclosed
US-20200270668-A1 REAGENTS AND METHODS FOR DETECTING ANALYTES BAYER HEALTHCARE, LLC 2020-08-27 — — US disclosed
US-10696998-B2 Reagents and methods for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2020-06-30 — — US disclosed
US-7163616-B2 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes BAYER CORPORATION (US) 2007-01-16 — — US disclosed
US-20030094384-A1 Reagents and methods for detecting analytes, and devices comprising reagents for detecting analytes ASCENSIA DIABETES CARE HOLDINGS AG (CH) 2003-05-22 — — US disclosed
EP-1293574-A2 Reagents, methods and devices for detecting analytes Bayer Corporation (US) 2003-03-19 — — EP disclosed
EP-0747984-B1 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof BAYER AG (US) 2002-08-14 — — EP disclosed
EP-0747984-A2 Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof Bayer Corporation (US) 1996-12-11 — — EP disclosed
US-5520786-A ELECTRODE SURFACE HAS BEEN IMPARTED BY A MEDIATOR FUNCTION COMPRISING ONE OR MORE MEDIATOR COMPOUNDS SELECTED FROM SUBSTITUTED OR UNSUBSTITUTED 3-PHENYLIMINO-3H-PHENOTHIAZINES AND 3-PHENYLIMINO-3H-PHENOXAZINES BAYER CORPORATION (US) 1996-05-28 — — US disclosed
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