Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 5/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | PNP | P00491 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4338534 | 0.87 | HAO1 (0.39) | HAO1MAPTHTTSLC6A9ALOX15 | |
| SCHEMBL4336068 | 0.81 | SLC6A9 (0.43) | HAO1HTTSLC6A9ALOX15 | |
| SCHEMBL4337657 | 0.80 | SLC6A9 (0.43) | HAO1MAPTHTTSLC6A9EPHX1 | |
| SCHEMBL4342646 | 0.77 | SLC6A9 (0.40) | HAO1MAPTSLC6A9PTGS1 | |
| SCHEMBL4347570 | 0.74 | PTGS1 (0.40) | HAO1MAPTSLC6A9PTGS1 | |
| SCHEMBL482240 | 0.72 | HAO1 (0.55) | HAO1EPHX1NOTUM | |
| SCHEMBL4337764 | 0.71 | HSD17B10 (0.59) | HAO1HTTSLC6A9ALOX15NQO2 | |
| SCHEMBL4328724 | 0.69 | SLC6A9 (0.43) | HAO1MAPTHTTSLC6A9ALOX15 | |
| SCHEMBL4338317 | 0.69 | ESR2 (0.49) | MAPTHTTSLC6A9ALOX15MCL1 | |
| SCHEMBL7938589 | 0.68 | PGR (0.46) | HAO1SLC6A9EPHX1NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612068-B2 | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | H. LUNDBECK A/S (DK) | 2009-11-03 | — | — | US | disclosed |
| CN-100439330-C | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | LUNDBECK & CO AS H (DK) | 2008-12-03 | — | — | CN | disclosed |
| CN-1780815-A | Aromatic oxyphenyl and aromatic sulfanylphenyl derivatives | LUNDBECK & CO AS H (DK) | 2006-05-31 | — | — | CN | disclosed |