SCHEMBL4336819

SCHEMBL4336819

CC(c1ccc(Cl)cc1)C(CC(C(=O)NO)c1nccs1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 8/20 0.47
CTSA P10619 6/20 0.44
LMNA P02545 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
INPPL1 O15357 1/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
TSHR P16473 1/20 0.39
PRCP P42785 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4341882 1.00 FFAR2 (0.47) FFAR2CTSALMNAMEN1KMT2A
SCHEMBL4340119 0.94 CYP1A2 (0.44) FFAR2CTSALMNACYP1A2CYP3A4
SCHEMBL4326210 0.91 CTSA (0.41) FFAR2CTSALMNACYP1A2CYP3A4
SCHEMBL4343417 0.91 CTSA (0.41) FFAR2CTSALMNACYP1A2CYP3A4
SCHEMBL4322303 0.90 SLC6A9 (0.48) CTSALMNAMEN1KMT2ACYP1A2
SCHEMBL4320523 0.90 SLC6A9 (0.48) CTSALMNAMEN1KMT2ACYP1A2
SCHEMBL4333128 0.89 CTSA (0.47) FFAR2CTSALMNAMEN1KMT2A
SCHEMBL4335210 0.89 CTSA (0.47) FFAR2CTSALMNAMEN1KMT2A
SCHEMBL4329554 0.85 CTSA (0.43) FFAR2CTSAINPPL1
SCHEMBL4331310 0.85 CTSA (0.43) FFAR2CTSAINPPL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7521563-B2 Hydroxamic acid derivative and medicine containing the same as active ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2009-04-21 US claimed
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US claimed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP claimed
US-7521563-B2 Hydroxamic acid derivative and medicine containing the same as active ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2009-04-21 US disclosed
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US disclosed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient IL6, IL1A, TNF FFAR2 1603/4885CTSA 1028/4885LMNA 4303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.