Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PTPRC | P08575 | 3/20 | 0.45 |
| ▸ | S100A4 | P26447 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3982285 | 0.83 | CA1 (0.47) | CA1CA2CA7CA9MAPT | |
| SCHEMBL22833739 | 0.81 | PNMT (0.45) | CA1CA2CA9MAPTTDP2 | |
| SCHEMBL29506344 | 0.81 | PNMT (0.45) | CA1CA2CA9MAPTTDP2 | |
| SCHEMBL8778972 | 0.81 | HTR2A (0.49) | CA1CA2CA7CA9MAPT | |
| SCHEMBL16559365 | 0.79 | MAPT (0.61) | CA1CA2CA7CA9MAPT | |
| SCHEMBL6841697 | 0.77 | ADRA2A (0.47) | CA1CA2CA7CA9MAPT | |
| SCHEMBL2061978 | 0.74 | PNMT (0.53) | MAPTTDP2MEN1KMT2ALMNA | |
| SCHEMBL568785 | 0.74 | BAZ1A (0.58) | CA1CA2CA7CA9MAPT | |
| SCHEMBL30954730 | 0.74 | BAZ1A (0.58) | CA1CA2CA7CA9MAPT | |
| SCHEMBL6840810 | 0.73 | SIGMAR1 (0.51) | CA1CA2CA7CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| WO-2009141096-A1 | SUBSTITUTED SPIRO-ISOXAZOLINES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |