Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGPL1 | O95470 | 4/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.57 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 4/20 | 0.57 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.57 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | TSPO | P30536 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.57 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.54 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29472620 | 1.00 | SGPL1 (0.58) | SGPL1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL20510812 | 1.00 | SGPL1 (0.58) | SGPL1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL195872 | 0.91 | SGPL1 (0.61) | SGPL1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL18286333 | 0.91 | SGPL1 (0.61) | SGPL1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL43371 | 0.91 | SGPL1 (0.61) | SGPL1S1PR1S1PR3S1PR2S1PR4 | |
| SCHEMBL13030814 | 0.82 | SGPL1 (0.66) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL8934971 | 0.82 | SGPL1 (0.66) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL1273298 | 0.80 | SGPL1 (0.63) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL861987 | 0.80 | SGPL1 (0.63) | SGPL1PLA2G4ALPAR5PTPN1LPAR6 | |
| SCHEMBL28255336 | 0.80 | CYP2D6 (0.56) | SGPL1PTPN1CYP2D6SPHK1GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113347978-B | Use of P1P derivatives as sepsis therapeutic agents | 埃克斯索生物制药有限公司 | 2024-06-07 | — | — | CN | claimed |
| US-20220079960-A1 | USE OF P1P DERIVATIVES AS THERAPEUTIC AGENT FOR SEPSIS | AXCESO BIOPHARMACO.,LTD. (KR) | 2022-03-17 | — | — | US | claimed |
| US-12590083-B2 | Inhibitors of spinster homolog 2 (SPNS2) for use in therapy | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2026-03-31 | — | — | US | disclosed |
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS INC (US) | 2025-10-16 | — | — | US | disclosed |
| EP-4522646-A2 | APOE LIPOPROTEIN SYSTEMS | Kisbee Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-4499052-A2 | SPHINGOLIPID-LOADED NANOBIOLOGICS FOR IMMUNE REGULATION | Icahn School of Medicine at Mount Sinai (US) | 2025-02-05 | — | — | EP | disclosed |
| EP-4465976-A1 | USES AND METHODS FOR PROMOTING INCREASED MITOCHONDRIAL MASS AND FUNCTION | Brightseed, Inc. (US) | 2024-11-27 | — | — | EP | disclosed |
| CN-113347978-B | Use of P1P derivatives as sepsis therapeutic agents | 埃克斯索生物制药有限公司 | 2024-06-07 | — | — | CN | disclosed |
| JP-2024015132-A | COMPOSITION COMPRISING O-CYCLIC PHYTOSPHINGOSINE-1-PHOSPHATE FOR PREVENTING OR TREATING PARKINSON'S DISEASE | エクセソ バイオファーマ カンパニー リミテッド | 2024-02-01 | — | — | JP | disclosed |
| WO-2023220387-A2 | APOE LIPOPROTEIN SYSTEMS | KISBEE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023210882-A1 | COMPOSITION FOR BOOSTING IMMUNITY AND PREVENTING, AMELIORATING, OR TREATING PARKINSON'S DISEASE, COMPRISING O-CYCLIC PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE AS ACTIVE INGREDIENT | 경상국립대학교산학협력단 | 2023-11-02 | — | — | WO | disclosed |
| EP-3995570-A1 | COMPOSITION FOR PROMOTING PROLIFERATION OF STEM CELLS, CONTAINING, AS ACTIVE INGREDIENT, CP1P OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | Industry-University Cooperation Foundation Hanyang University (KR) | 2022-05-11 | — | — | EP | disclosed |
| WO-2022081567-A1 | METHODS FOR REVERSING HEPATIC STEATOSIS | BRIGHTSEED, INC. (US) | 2022-04-21 | — | — | WO | disclosed |
| US-20220089581-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-03-24 | — | — | US | disclosed |
| US-20220079960-A1 | USE OF P1P DERIVATIVES AS THERAPEUTIC AGENT FOR SEPSIS | AXCESO BIOPHARMACO.,LTD. (KR) | 2022-03-17 | — | — | US | disclosed |
| CN-114127264-A | Composition for promoting stem cell proliferation comprising cyclic phytosphingosine-1-phosphate or pharmaceutically acceptable salt thereof as active ingredient | 汉阳大学校产学协力团 | 2022-03-01 | — | — | CN | disclosed |
| US-9783562-B2 | Phytosphingosine-1-phosphate derivative, preparation method therefor, and composition for preventing and treating hair loss or for growing hair comprising same | PHYTOS CO., LTD (KR) | 2017-10-10 | — | — | US | disclosed |
| US-9783562-B2 | Phytosphingosine-1-phosphate derivative, preparation method therefor, and composition for preventing and treating hair loss or for growing hair comprising same | PHYTOS CO., LTD (KR) | 2017-10-10 | — | — | US | disclosed |
| US-20160046656-A1 | NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME | PHYTOS CO., LTD. (KR) | 2016-02-18 | — | — | US | disclosed |
| US-20160046656-A1 | NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME | PHYTOS CO., LTD. (KR) | 2016-02-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220089581-A1 | INHIBITORS OF SPINSTER HOMOLOG 2 (SPNS2) FOR USE IN THERAPY | SPNS2, SPCS2, SMN1; SMN2 | SGPL1 146/4885S1PR1 473/4885S1PR3 610/4885 |
| US-20250319190-A1 | APOE LIPOPROTEIN SYSTEMS | APOB, APOL1, LDLR | SGPL1 191/4885S1PR1 685/4885S1PR3 782/4885 |
| US-20220079960-A1 | USE OF P1P DERIVATIVES AS THERAPEUTIC AGENT FOR SEPSIS | SIRT1, SELP, VASP | SGPL1 259/4885S1PR1 78/4885S1PR3 181/4885 |
| US-20160046656-A1 | NOVEL PHYTOSPHINGOSINE-1-PHOSPHATE DERIVATIVE, PREPARATION METHOD THEREFOR, AND COMPOSITION FOR PREVENTING AND TREATING HAIR LOSS OR FOR GROWING HAIR COMPRISING SAME | SGPL1, DCTPP1, PSAP | SGPL1 1/4885S1PR1 16/4885S1PR3 65/4885 |
| US-12590083-B2 | Inhibitors of spinster homolog 2 (SPNS2) for use in therapy | SPNS2, SLC20A2, S1PR2 | SGPL1 56/4885S1PR1 9/4885S1PR3 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.