SCHEMBL433742

SCHEMBL433742

O=C(O)CCCCCCCCCCCCCCCCC(=O)N[C@@H](CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)ON1C(=O)CCC1=O)C(=O)O

nearest known ligand 0.55

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 8/20 0.55
FOLH1 Q04609 2/20 0.41
CCKAR P32238 7/20 0.40
CCKBR P32239 7/20 0.40
GLO1 Q04760 1/20 0.39
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7953485 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL15428776 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL18379187 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL7947055 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL2151921 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL20608169 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL12276299 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL12275938 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL1893405 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1
SCHEMBL2435629 1.00 GLP1R (0.55) GLP1RFOLH1CCKARCCKBRGLO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421289-B2 GLP-1 analogues SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2025-09-23 US disclosed
CN-119978139-A Fusion polypeptide and method for preparing target polypeptide by using same 浙江泽瑞生物医药有限公司 2025-05-13 CN disclosed
CN-106139158-B Growth hormone with prolonged in vivo efficacy 诺沃—诺迪斯克保健股份有限公司 2024-06-21 CN disclosed
US-20240199718-A1 GLP-1 Analogues SUN PHARMACEUTICAL IND LTD (IN) 2024-06-20 US disclosed
EP-4364751-A2 NOVEL GLP-1 ANALOGUES Sun Pharmaceutical Industries Limited (IN) 2024-05-08 EP disclosed
EP-4122954-B1 NOVEL GLP-1 ANALOGUES SUN PHARMACEUTICAL IND LTD (IN) 2024-04-03 EP disclosed
US-11873328-B2 GLP-1 analogues SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-01-16 US disclosed
US-11866477-B2 GLP-1 analogues SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2024-01-09 US disclosed
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF NOVO NORDISK AS (DK) 2023-11-16 US disclosed
US-11787837-B2 DCHBS-active esters of PEG compounds and their use NOVO NORDISK A/S (DK) 2023-10-17 US disclosed
WO-2011101277-A1 CONJUGATED PROTEINS NOVO NORDISK A/S (DK) 2011-08-25 WO disclosed
WO-2011089255-A1 GROWTH HORMONES WITH PROLONGED IN-VIVO EFFICACY NOVO NORDISK HEALTH CARE AG (CH) 2011-07-28 WO disclosed
EP-2340049-A1 METHOD OF ACYLATING A PEPTIDE OR PROTEIN Novo Nordisk A/S (DK) 2011-07-06 EP disclosed
WO-2010142665-A1 GLP-1 AND FGF21 COMBINATIONS FOR TREATMENT OF DIABETES TYPE 2 NOVO NORDISK A/S (DK) 2010-12-16 WO disclosed
US-20100317057-A1 SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES NOVO NORDISK A/S (DK) 2010-12-16 US disclosed
US-20100216715-A1 FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use NOVO NORDISK A/S (DK) 2010-08-26 US disclosed
WO-2010084169-A2 FGF21 DERIVATIVES WITH ALBUMIN BINDER A-B-C-D-E- AND THEIR USE NOVO NORDISK A/S (DK) 2010-07-29 WO disclosed
WO-2010084169-A2 FGF21 DERIVATIVES WITH ALBUMIN BINDER A-B-C-D-E- AND THEIR USE NOVO NORDISK A/S (DK) 2010-07-29 WO disclosed
WO-2010029159-A1 METHOD OF ACYLATING A PEPTIDE OR PROTEIN NOVO NORDISK A/S (DK) 2010-03-18 WO disclosed
WO-2009083549-A1 SEMI-RECOMBINANT PREPARATION OF GLP-1 ANALOGUES NOVO NORDISK A/S (DK) 2009-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100216715-A1 FGF21 Derivatives With Albumin Binder A-B-C-D-E- And Their Use FABP1, FABP4, FGFR1 GLP1R 45/4885FOLH1 1037/4885CCKAR 729/4885
US-20230364248-A1 MIC-1 COMPOUNDS AND USES THEREOF IMMT, MICA, TAP1 GLP1R 710/4885FOLH1 1511/4885CCKAR 1112/4885
US-12421289-B2 GLP-1 analogues GLP1R, GIPR, GPR119 GLP1R 1/4885FOLH1 508/4885CCKAR 30/4885
US-20240199718-A1 GLP-1 Analogues GLP1R, GIPR, GPR119 GLP1R 1/4885FOLH1 508/4885CCKAR 30/4885
US-11873328-B2 GLP-1 analogues GLP1R, GIPR, GPR119 GLP1R 1/4885FOLH1 508/4885CCKAR 30/4885
US-11866477-B2 GLP-1 analogues GLP1R, GIPR, GPR119 GLP1R 1/4885FOLH1 508/4885CCKAR 30/4885
US-11787837-B2 DCHBS-active esters of PEG compounds and their use HBB, IAPP, GLP1R GLP1R 3/4885FOLH1 2215/4885CCKAR 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.