Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.65 |
| ▸ | RXRA | P19793 | 13/20 | 0.64 |
| ▸ | RXRB | P28702 | 13/20 | 0.64 |
| ▸ | RXRG | P48443 | 10/20 | 0.64 |
| ▸ | NR4A2 | P43354 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | C5 | P01031 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4320438 | 0.94 | RXRA (0.70) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4337631 | 0.90 | RXRA (0.61) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4330498 | 0.88 | RXRA (0.59) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4335073 | 0.87 | RXRA (0.59) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4327894 | 0.86 | RXRA (0.83) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4333227 | 0.85 | FAAH (0.61) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4323846 | 0.84 | RXRA (0.53) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4322068 | 0.84 | RXRA (0.54) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL4341788 | 0.84 | RXRA (0.54) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 | |
| SCHEMBL7502488 | 0.83 | RXRA (0.58) | KDM4ECYP3A4CYP2C19MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7521563-B2 | Hydroxamic acid derivative and medicine containing the same as active ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2009-04-21 | — | — | US | disclosed |
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1787986-A1 | HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT | SHIZUOKA COFFEIN CO., LTD. (JP) | 2007-05-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208065-A1 | Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient | IL6, IL1A, TNF | KDM4E 1921/4885CYP3A4 2548/4885CYP2C19 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.