Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.61 |
| ▸ | ACR | P10323 | 2/20 | 0.61 |
| ▸ | ATP4A | P20648 | 14/20 | 0.59 |
| ▸ | ATP4B | P51164 | 14/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 2/20 | 0.59 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4331865 | 0.87 | ATP4A (0.76) | PRSS1ACRATP4AATP4BMAPT | |
| SCHEMBL4329794 | 0.86 | ATP4A (0.66) | PRSS1ACRATP4AATP4BMAPT | |
| SCHEMBL4333577 | 0.84 | MAPT (0.53) | PRSS1ACRMAPTNPC1RAB9A | |
| SCHEMBL4324204 | 0.82 | ATP4A (0.55) | PRSS1ATP4AATP4BMAPTNPC1 | |
| SCHEMBL4333457 | 0.82 | ATP4A (0.57) | ATP4AATP4BMAPTNPC1RAB9A | |
| SCHEMBL4326705 | 0.82 | ATP4A (0.55) | PRSS1ACRATP4AATP4BMAPT | |
| SCHEMBL4322678 | 0.81 | ATP4A (0.70) | PRSS1ACRATP4AATP4BMAPT | |
| SCHEMBL4334951 | 0.80 | ATP4A (0.58) | ATP4AATP4BMAPTNPC1RAB9A | |
| SCHEMBL4330728 | 0.79 | ADORA3 (0.48) | PRSS1ACRMAPTNPC1RAB9A | |
| SCHEMBL4109611 | 0.75 | ATP4A (1.00) | ATP4AATP4BMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |