Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | PHGDH | O43175 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATP4A | P20648 | 2/20 | 0.43 |
| ▸ | ATP4B | P51164 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4334954 | 0.89 | MAPT (0.52) | MEN1KMT2AALDH1A1RAB9AHTT | |
| SCHEMBL4338179 | 0.81 | ATP4A (0.61) | NPC1RAB9AMAPTATP4AATP4B | |
| SCHEMBL4324085 | 0.79 | PHGDH (0.50) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4322757 | 0.79 | GSTO1 (0.51) | MEN1KMT2ARAB9ASMN1; SMN2MAPT | |
| SCHEMBL3613302 | 0.78 | ALDH1A1 (0.72) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4330190 | 0.77 | KCNQ1 (0.53) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3608913 | 0.77 | CCR4 (0.55) | KMT2AALDH1A1RAB9AHPGDHTT | |
| SCHEMBL3612059 | 0.74 | MAPT (0.52) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL4330728 | 0.72 | ADORA3 (0.48) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL3604035 | 0.72 | ATP4A (0.56) | MEN1KMT2AALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | claimed |
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |