SCHEMBL562017

SCHEMBL562017

O=C(Nn1cncn1)c1ccccc1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.50
ALDH1A1 P00352 4/20 0.50
MEN1 O00255 4/20 0.50
HPGD P15428 4/20 0.50
KMT2A Q03164 4/20 0.50
USP2 O75604 1/20 0.50
MAPT P10636 1/20 0.50
PTGS1 P23219 1/20 0.49
PTGS2 P35354 1/20 0.49
SMN1; SMN2 Q16637 3/20 0.47
GAA P10253 2/20 0.47
MPO P05164 1/20 0.47
HIF1A Q16665 1/20 0.47
LMNA P02545 5/20 0.44
HTT P42858 4/20 0.44
TP53 P04637 3/20 0.44
HSD17B10 Q99714 3/20 0.44
NPC1 O15118 2/20 0.44
POLB P06746 2/20 0.42
ALPL P05186 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6663174 0.79 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2GAALMNAHTT
SCHEMBL4338282 0.75 KDM4E (0.50) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL11033030 0.73 KMT2A (0.68) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL10635304 0.72 KDM4E (0.50) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL5924206 0.71 HDAC6 (0.35) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL10563462 0.69 KDM4E (0.52) KDM4EMEN1KMT2AUSP2MAPT
SCHEMBL11339136 0.68 KDM4E (0.65) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL77381 0.67 CA1 (0.77) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL70688 0.67 KDM4E (0.71) KDM4EALDH1A1MEN1HPGDKMT2A
SCHEMBL15033508 0.67 KDM4E (1.00) KDM4EALDH1A1MEN1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5096951-A Calcium hydroxystearate, 3-salicyloylamido-1,2,4-triazole or tris-2-tert butyl-4-thio-/2'-methyl-4'-hydroxy-5'-tert butyl/ phenyl-5-methyl phenyl phosphite metal deactivator; molded parts HOECHST CELANESE CORPORATION (US) 1992-03-17 US claimed
US-20250263524-A1 Method for Polycondensation of a Recycled Polyester SI GROUP, INC. 2025-08-21 US disclosed
WO-2024133667-A1 A METHOD FOR IMPROVING THE PROCESSING OF POLYETHYLENE BASF SE (DE) 2024-06-27 WO disclosed
EP-3425001-B1 CYCLIC OLEFIN COPOLYMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF MITSUI CHEMICALS INC (JP) 2021-03-24 EP disclosed
CN-104508031-B Phosphite compositions 瑞士新集团有限公司 2020-10-16 CN disclosed
EP-2880092-B1 PHOSPHITE COMPOSITIONS SI GROUP SWITZERLAND CHAA GMBH (CH) 2020-09-30 EP disclosed
US-10662321-B2 Cyclic olefin copolymer composition and cross-linked product thereof MITSUI CHEMICALS, INC. (JP) 2020-05-26 US disclosed
US-10442900-B2 Mixed phosphite stabilization of polyethylene film NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2019-10-15 US disclosed
EP-3425001-A1 CYCLIC OLEFIN COPOLYMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF Mitsui Chemicals, Inc. (JP) 2019-01-09 EP disclosed
EP-2459576-B1 LIQUID ALKYLATED TRISARYL PHOSPHITE COMPOSITIONS HAVING TWO ALKYL GROUPS WITH DIFFERENT CARBON NUMBER ADDIVANT SWITZERLAND GMBH (CH) 2018-11-21 EP disclosed
US-5141975-A Melt processability, discoloration inhibition GENERAL ELECTRIC COMPANY (US) 1992-08-25 US disclosed
US-5137950-A Reacting phosphorous trichloride with alcohol; polymer stabilizer BORG-WARNER SPECIALTY CHEMICALS, INC. (US) 1992-08-11 US disclosed
US-5124472-A From tetrahydroabiethyl alcohol GENERAL ELECTRIC COMPANY (US) 1992-06-23 US disclosed
US-5096951-A Calcium hydroxystearate, 3-salicyloylamido-1,2,4-triazole or tris-2-tert butyl-4-thio-/2'-methyl-4'-hydroxy-5'-tert butyl/ phenyl-5-methyl phenyl phosphite metal deactivator; molded parts HOECHST CELANESE CORPORATION (US) 1992-03-17 US disclosed
US-5096951-A Calcium hydroxystearate, 3-salicyloylamido-1,2,4-triazole or tris-2-tert butyl-4-thio-/2'-methyl-4'-hydroxy-5'-tert butyl/ phenyl-5-methyl phenyl phosphite metal deactivator; molded parts HOECHST CELANESE CORPORATION (US) 1992-03-17 US disclosed
EP-0460461-A1 Hydrolytically stable phosphites GENERAL ELECTRIC COMPANY (US) 1991-12-11 EP disclosed
US-5023285-A Melt flow and color stabilizers for polymers G E SPECIALTY CHEMICALS (US) 1991-06-11 US disclosed
EP-0356687-A1 Bis (tri-tertiary-alkylphenoxy) diphosphaspiroundecanes GE SPECIALTY CHEMICALS, INC. (US) 1990-03-07 EP disclosed
EP-0356688-A2 3, 9-diphosphaspiroundecanes and process for making 3, 9-diphosphaspiroundecanes GE SPECIALTY CHEMICALS, INC. (US) 1990-03-07 EP disclosed
US-4233209-A Hindered phenol hydrazones and compositions stabilized therewith CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed