SCHEMBL6920212

SCHEMBL6920212

O=C(NN1CC=CS1)c1ccccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.49
HPGD P15428 6/20 0.49
ALDH1A1 P00352 5/20 0.49
MEN1 O00255 3/20 0.49
KMT2A Q03164 3/20 0.49
MAPT P10636 2/20 0.49
USP2 O75604 1/20 0.49
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
GAA P10253 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
MPO P05164 1/20 0.46
HIF1A Q16665 1/20 0.46
HTT P42858 7/20 0.42
LMNA P02545 6/20 0.42
HSD17B10 Q99714 4/20 0.42
TP53 P04637 3/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 2/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4338282 0.68 KDM4E (0.50) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL11339136 0.67 KDM4E (0.65) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL77381 0.66 CA1 (0.77) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL70688 0.66 KDM4E (0.71) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL11033030 0.66 KMT2A (0.68) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL15033508 0.66 KDM4E (1.00) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL577155 0.65 PTGS1 (1.00) KDM4EHPGDALDH1A1MEN1KMT2A
SCHEMBL562017 0.65 KDM4E (0.50) KDM4EHPGDALDH1A1MEN1KMT2A
Salicylhydroxamic Acid SCHEMBL144849 0.65 KDM4E (1.00) KDM4EHPGDALDH1A1MEN1KMT2A
Salicylhydroxamic Acid SCHEMBL21530845 0.65 KDM4E (1.00) KDM4EHPGDALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030042466-A1 ENHANCED OXIDATION RESISTANT POLYMERIC INSULATION COMPOSITION FOR AIR-COOLED GENERATORS SIEMENS WESTINGHOUSE POWER CORPORATION 2003-03-06 US claimed
US-6680119-B2 EPOXY-ANHYDRIDE RESIN THAT HAS BEEN PREREACTED WITH AN ANTIOXIDANT OLIGOMER SIEMENS WESTINGHOUSE POWER CORPORATION 2004-01-20 US disclosed
US-6555023-B2 Epoxy-anhydride resin is prereacted with an antioxidant oligomer that is organophosphorus compound, hindered alkylated phenolic, alkyl or aryl thioester or thiophosphite, thiazole, lactone, hydroxyalkylamine, or maleimide SIEMENS WESTINGHOUSE POWER CORPORATION 2003-04-29 US disclosed
US-20030042466-A1 ENHANCED OXIDATION RESISTANT POLYMERIC INSULATION COMPOSITION FOR AIR-COOLED GENERATORS SIEMENS WESTINGHOUSE POWER CORPORATION 2003-03-06 US disclosed
US-20030044605-A1 Insulated electrical coil having enhanced oxidation resistant polymeric insulation composition SIEMENS WESTINGHOUSE POWER CORPORATION 2003-03-06 US disclosed