SCHEMBL4338765

SCHEMBL4338765

CC(CCC(C(=O)NO)c1ncco1)c1ccc(Br)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR2 O15552 1/20 0.36
MMP1 P03956 3/20 0.33
MMP2 P08253 3/20 0.33
MMP3 P08254 3/20 0.33
MMP7 P09237 3/20 0.33
MMP9 P14780 2/20 0.33
MMP13 P45452 2/20 0.33
ALOX5 P09917 1/20 0.33
CYP1A2 P05177 1/20 0.33
CHRM1 P11229 1/20 0.32
PDE4A P27815 1/20 0.32
CTSA P10619 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
CNR1 P21554 1/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4336867 0.89 TSHR (0.38) MMP1MMP2MMP3MMP7CYP1A2
SCHEMBL4329564 0.88 CTSA (0.36) ALOX5CTSASMN1; SMN2KDM4EALDH1A1
SCHEMBL4320658 0.84 MEN1 (0.40) CTSASMN1; SMN2ALDH1A1
SCHEMBL4320613 0.76 FFAR2 (0.38) FFAR2MMP2MMP3MMP7CYP1A2
SCHEMBL4327553 0.76 CTSA (0.41) CTSA
SCHEMBL4327095 0.72 CTSA (0.39) FFAR2MMP1MMP2MMP3MMP7
SCHEMBL4339970 0.71 MMP1 (0.38) FFAR2MMP1MMP2MMP3MMP7
SCHEMBL4335154 0.71 TDP1 (0.40) CTSASMN1; SMN2KDM4EALDH1A1
SCHEMBL4334429 0.71 MMP1 (0.38) MMP1MMP2MMP3MMP7MMP9
SCHEMBL4325351 0.71 HDAC3 (0.39) CTSA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US claimed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP claimed
US-7521563-B2 Hydroxamic acid derivative and medicine containing the same as active ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2009-04-21 US disclosed
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient SHIZUOKA COFFEIN CO., LTD. (JP) 2007-09-06 US disclosed
EP-1787986-A1 HYDROXAMIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME AS ACTIVE INGREDIENT SHIZUOKA COFFEIN CO., LTD. (JP) 2007-05-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208065-A1 Hydroxamic Acid Derivative and Medicine Containing the Same as Active Ingredient IL6, IL1A, TNF FFAR2 1603/4885MMP1 71/4885MMP2 319/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.