⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792773 | 0.94 | — | — | |
| SCHEMBL17681537 | 0.91 | ACHE (0.33) | — | |
| SCHEMBL11797630 | 0.88 | — | — | |
| SCHEMBL14958119 | 0.85 | — | — | |
| SCHEMBL10438886 | 0.85 | CYP1A2 (0.34) | — | |
| SCHEMBL11792245 | 0.83 | — | — | |
| SCHEMBL11793431 | 0.83 | ALDH1A1 (0.42) | — | |
| SCHEMBL2338466 | 0.82 | HDAC3 (0.41) | — | |
| SCHEMBL26992749 | 0.82 | MGLL (0.47) | — | |
| SCHEMBL11866891 | 0.82 | L3MBTL1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629430-B2 | Hybrid silicon-containing coupling agents for filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-08 | — | — | US | claimed |
| US-20070185279-A1 | Hydrolysis; dehydrogenation; improved performance | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-08-09 | — | — | US | claimed |
| US-7169872-B2 | Hybrid silicon-containing coupling agents for filled elastomer compositions | GENERAL ELECTRIC CO. (US) | 2007-01-30 | — | — | US | claimed |
| CN-1610687-A | Hybrid silicon-containing coupling agents for filled elastomer compositions | CROMPTON CORP (US) | 2005-04-27 | — | — | CN | claimed |
| EP-1383776-A2 | HYBRID SILICON-CONTAINING COUPLING AGENTS FOR FILLED ELASTOMER COMPOSITIONS | CROMPTON CORPORATION (US) | 2004-01-28 | — | — | EP | claimed |
| US-20030055139-A1 | Hybrid silicon-containing coupling agents for filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2003-03-20 | — | — | US | claimed |
| WO-2002096914-A2 | HYBRID SILICON-CONTAINING COUPLING AGENTS FOR FILLED ELASTOMER COMPOSITIONS | CROMPTON CORPORATION (US) | 2002-12-05 | — | — | WO | claimed |
| US-7629430-B2 | Hybrid silicon-containing coupling agents for filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2009-12-08 | — | — | US | disclosed |
| US-7301042-B2 | Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-11-27 | — | — | US | disclosed |
| US-20070185279-A1 | Hydrolysis; dehydrogenation; improved performance | MOMENTIVE PERFORMANCE MATERIALS INC. | 2007-08-09 | — | — | US | disclosed |
| US-7169872-B2 | Hybrid silicon-containing coupling agents for filled elastomer compositions | GENERAL ELECTRIC CO. (US) | 2007-01-30 | — | — | US | disclosed |
| EP-1529073-A1 | BLOCKED MERCAPTOSILANE HYDROLYZATES AS COUPLING AGENTS FOR MINERAL-FILLED ELASTOMER COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2005-05-11 | — | — | EP | disclosed |
| CN-1610687-A | Hybrid silicon-containing coupling agents for filled elastomer compositions | CROMPTON CORP (US) | 2005-04-27 | — | — | CN | disclosed |
| EP-1383776-A2 | HYBRID SILICON-CONTAINING COUPLING AGENTS FOR FILLED ELASTOMER COMPOSITIONS | CROMPTON CORPORATION (US) | 2004-01-28 | — | — | EP | disclosed |
| WO-2003091314-A1 | BLOCKED MERCAPTOSILANE HYDROLYZATES AS COUPLING AGENTS FOR MINERAL-FILLED ELASTOMER COMPOSITIONS | GENERAL ELECTRIC COMPANY (US) | 2003-11-06 | — | — | WO | disclosed |
| US-20030199619-A1 | Blocked mercaptosilane hydrolyzates as coupling agents for mineral-filled elastomer compositions | CROMPTON CORPORATION | 2003-10-23 | — | — | US | disclosed |
| US-20030055139-A1 | Hybrid silicon-containing coupling agents for filled elastomer compositions | MOMENTIVE PERFORMANCE MATERIALS INC. | 2003-03-20 | — | — | US | disclosed |
| WO-2002096914-A2 | HYBRID SILICON-CONTAINING COUPLING AGENTS FOR FILLED ELASTOMER COMPOSITIONS | CROMPTON CORPORATION (US) | 2002-12-05 | — | — | WO | disclosed |