Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.48 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272101 | 0.78 | KDM4E (0.62) | KDM4EHSD17B10CYP1A2LMNACYP2C9 | |
| SCHEMBL23318966 | 0.78 | HIF1A (0.72) | HTTKDM4EHSD17B10CYP1A2LMNA | |
| SCHEMBL23040669 | 0.77 | KDM4E (0.60) | KDM4EHSD17B10CYP1A2LMNACYP2C9 | |
| SCHEMBL18740836 | 0.76 | KDM4E (0.57) | KDM4EHSD17B10CYP1A2LMNACYP2C9 | |
| SCHEMBL23318541 | 0.76 | ADRB2 (0.57) | KDM4EHSD17B10CYP1A2LMNACYP2C9 | |
| SCHEMBL18740843 | 0.76 | SLC22A3 (0.56) | KDM4EHSD17B10CYP1A2LMNATDP1 | |
| SCHEMBL31748897 | 0.75 | HIF1A (0.81) | KDM4EHSD17B10CYP1A2LMNACYP2C9 | |
| SCHEMBL10481814 | 0.75 | HIF1A (0.81) | KDM4EHSD17B10CYP1A2LMNACYP2C9 | |
| SCHEMBL4632760 | 0.74 | ADRB2 (0.52) | CYP1A2TDP1ADRB2HIF1ATSHR | |
| SCHEMBL17253654 | 0.74 | TSHR (0.67) | KDM4EHSD17B10CYP1A2LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2021502-A1 | NOVEL GENES AND MARKERS IN TYPE 2 DIABETES AND OBESITY | Oy Jurilab Ltd (FI) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007128884-A1 | NOVEL GENES AND MARKERS IN TYPE 2 DIABETES AND OBESITY | OY JURILAB LTD (FI) | 2007-11-15 | — | — | WO | disclosed |