Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.32 |
| ▸ | HTR2A | P28223 | 9/20 | 0.32 |
| ▸ | HTR2B | P41595 | 9/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1013730 | 0.76 | HTR2C (0.38) | HTR2CHTR2AHTR2B | |
| SCHEMBL4195565 | 0.76 | DYRK1A (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL4198092 | 0.76 | ADCY6 (0.34) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL30170812 | 0.74 | DYRK1A (0.34) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL1017059 | 0.74 | HTR2C (0.37) | HTR2CHTR2AHTR2B | |
| SCHEMBL15001479 | 0.69 | HTR7 (0.51) | HTR2CHTR2AHTR2B | |
| Hydrochloric Acid SCHEMBL14991041 | 0.68 | HTR7 (0.50) | HTR2CHTR2AHTR2B | |
| SCHEMBL12333209 | 0.68 | HTR2A (0.35) | HTR2CHTR2AHTR2B | |
| SCHEMBL2339507 | 0.67 | HTR2A (0.65) | HTR2CHTR2AHTR2B | |
| SCHEMBL19711567 | 0.67 | PNMT (0.32) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2024368-A2 | 6,7,8,9-TETRAHYDRO-5H-PYRIMIDO[4,5-D]AZEPIN-4-YL]-AMINE DERIVATIVES AS MODULATORS OF TRPV1 FOR THE TREATMENT OF PAIN | Janssen Pharmaceutica, N.V. (BE) | 2009-02-18 | — | — | EP | claimed |
| WO-2007109355-A2 | 6,7,8, 9 -TETRAHYDRO- 5H- PYRIMIDO [4, 5-D] AZEPIN-4-YL] -AMINE DERIVATIVES AS MODULATORS OF TRPVL FOR THE TREATMENT OF PAIN | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-09-27 | — | — | WO | claimed |