SCHEMBL4339977

SCHEMBL4339977

CC(=O)O[C@H]1C[C@H](n2ccc(=O)[nH]c2=O)O[C@@H]1CO

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RNASE1 P07998 1/20 0.53
SLC28A1 O00337 1/20 0.49
SLC28A2 O43868 1/20 0.49
SLC29A1 Q99808 1/20 0.49
SLC28A3 Q9HAS3 1/20 0.49
DUT P33316 3/20 0.46
POLB P06746 1/20 0.45
SLC6A2 P23975 1/20 0.43
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
TK1 P04183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13626717 1.00 RNASE1 (0.53) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL13626065 1.00 RNASE1 (0.53) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL4339980 1.00 RNASE1 (0.53) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL19813627 0.91 RNASE1 (0.53) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL13626718 0.90 DUT (0.46) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL13637227 0.90 DUT (0.46) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL19813629 0.90 RNASE1 (0.54) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL19813632 0.90 RNASE1 (0.54) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL12930558 0.89 DUT (0.47) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3
SCHEMBL13901234 0.89 RNASE1 (0.52) RNASE1SLC28A1SLC28A2SLC29A1SLC28A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250283094-A1 Modified Nucleosides SOMALOGIC OPERATING CO., INC. (US) 2025-09-11 US disclosed
EP-4323374-A1 MODIFIED NUCLEOSIDES SomaLogic Operating Co., Inc. (US) 2024-02-21 EP disclosed
WO-2022221241-A1 MODIFIED NUCLEOSIDES SOMALOGIC OPERATING CO., INC. (US) 2022-10-20 WO disclosed
EP-2123759-A2 Stabilized RNAS as transfection controls and silencing reagents Dharmacon, Inc. (US) 2009-11-25 EP disclosed
US-20090280567-A1 STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS DHARMACON, INC. (US) 2009-11-12 US disclosed
EP-1718747-B1 STABILIZED RNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS DHARMACON INC (US) 2009-10-28 EP disclosed
US-20070269889-A1 Stabilized siRNAs as transfection controls and silencing reagents DHARMACON, INC. (US) 2007-11-22 US disclosed
EP-1718747-A2 STABILIZED RNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS Dharmacon, Inc. (US) 2006-11-08 EP disclosed
WO-2005078094-A2 STABILIZED RNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS DHARMACON, INC. (US) 2005-08-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090280567-A1 STABILIZED SIRNAS AS TRANSFECTION CONTROLS AND SILENCING REAGENTS PHAX, NSUN2, UPF1 RNASE1 220/4885SLC28A1 276/4885SLC28A2 271/4885
US-20250283094-A1 Modified Nucleosides NT5C3B, PNP, TYMP RNASE1 174/4885SLC28A1 72/4885SLC28A2 76/4885
US-20070269889-A1 Stabilized siRNAs as transfection controls and silencing reagents PHAX, NSUN2, UPF1 RNASE1 220/4885SLC28A1 276/4885SLC28A2 271/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.