Aminodiphenylmethane

Aminodiphenylmethane

SCHEMBL4340486

C=Cc1ccccc1.NC(c1ccccc1)c1ccccc1

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
TSHR P16473 1/20 0.64
DPP4 P27487 2/20 0.44
F2 P00734 1/20 0.44
ADRA2A P08913 1/20 0.40
ADRA2C P18825 1/20 0.40
LMNA P02545 1/20 0.40
HIF1A Q16665 1/20 0.40
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminodiphenylmethane SCHEMBL9499747 0.95 ALDH1A1 (0.56) ALDH1A1TSHRDPP4F2ADRA2A
Styrene SCHEMBL7656757 0.87 ALDH1A1 (0.48) ALDH1A1TSHRDPP4F2ADRA2A
Hydrochloric Acid SCHEMBL5493381 0.83 ALDH1A1 (0.43) ALDH1A1TSHRDPP4F2ADRA2A
Aminodiphenylmethane SCHEMBL7897875 0.82 ALDH1A1 (0.48) ALDH1A1TSHRDPP4F2ADRA2A
Styrene SCHEMBL11034121 0.81 ALDH1A1 (0.70) ALDH1A1TSHRADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL11059631 0.81 DPP4 (0.48) ALDH1A1DPP4F2ADRA2AADRA2C
Styrene SCHEMBL21485240 0.80 ALDH1A1 (0.88) ALDH1A1TSHRLMNA
Styrene SCHEMBL10892600 0.80 ALDH1A1 (1.00) ALDH1A1TSHRLMNA
Styrene SCHEMBL4986035 0.80 ALDH1A1 (1.00) ALDH1A1TSHRLMNA
Styrene SCHEMBL11144289 0.80 ALDH1A1 (1.00) ALDH1A1TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0758250-A1 TEXAPHYRIN SOLID-SUPPORTS AND DEVICES THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1997-02-19 EP claimed
US-5594136-A USEFUL IN THE SEPARATION OF NEUTRAL AND ANIONIC SPECIES, PHOSPHATE ESTER HYDROLYSIS, MAGNETIC RESONANCE IMAGING AND PHOTODYNAMIC THERAPY PHARMACYCLICS, INC. (US) 1997-01-14 US claimed
WO-1995029702-A1 TEXAPHYRIN SOLID-SUPPORTS AND DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-11-09 WO claimed
JP-59186947-A None JP disclosed
US-20090298048-A1 NON-FLUORESCENT, NON-ENZYMATIC, CHEMILUMINESCENT AQUEOUS ASSAY INTEGRIGEN, INC. (US) 2009-12-03 US disclosed
US-20090208451-A1 HALOGEN PHOSPHONATE MONOESTERS INTEGRIGEN, INC. (US) 2009-08-20 US disclosed
US-20070249820-A1 Activatable Ribozymal Purification Constructs and Methods of Use THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2007-10-25 US disclosed
WO-2005067665-A2 ACTIVATABLE RIBOZYMAL PURIFICATION CONSTRUCTS AND METHODS OF USE UNIVERSITY OF COLORADO (US) 2005-07-28 WO disclosed
WO-2005037228-A2 HALOGEN PHOSPHONATE MONOESTERS INTEGRIGEN, INC. (US) 2005-04-28 WO disclosed
EP-0758250-A1 TEXAPHYRIN SOLID-SUPPORTS AND DEVICES THE BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1997-02-19 EP disclosed
US-5594136-A USEFUL IN THE SEPARATION OF NEUTRAL AND ANIONIC SPECIES, PHOSPHATE ESTER HYDROLYSIS, MAGNETIC RESONANCE IMAGING AND PHOTODYNAMIC THERAPY PHARMACYCLICS, INC. (US) 1997-01-14 US disclosed
WO-1995029702-A1 TEXAPHYRIN SOLID-SUPPORTS AND DEVICES BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 1995-11-09 WO disclosed
EP-0181236-B1 LHRH ANALOGUES USEFUL IN STIMULATING ANTI-LHRH ANTIBODIES AND VACCINES CONTAINING SUCH ANALOGUES PITMAN-MOORE, INC. (US) 1991-10-09 EP disclosed
US-4608251-A ANTIFERILITY AGENTS PITMAN-MOORE, INC. (US) 1986-08-26 US disclosed
JP-S59186947-A NOVEL PEPTIDE KOWA CO 1984-10-23 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090208451-A1 HALOGEN PHOSPHONATE MONOESTERS FCGRT, PTMS, DNPEP ALDH1A1 2586/4885TSHR 217/4885DPP4 331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.