Aminodiphenylmethane

Aminodiphenylmethane

SCHEMBL11059631

C=CC.NC(c1ccccc1)c1ccccc1

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.48
F2 P00734 1/20 0.48
ADRA2A P08913 1/20 0.43
ADRA2C P18825 1/20 0.43
LMNA P02545 1/20 0.43
HIF1A Q16665 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ALDH1A1 P00352 1/20 0.41
TAAR1 Q96RJ0 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aminodiphenylmethane SCHEMBL7841 0.84 DPP4 (0.65) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL7897875 0.81 ALDH1A1 (0.48) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL4340486 0.81 ALDH1A1 (0.64) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL9499747 0.81 ALDH1A1 (0.56) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL8686295 0.81 DPP4 (0.61) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL9596876 0.81 DPP4 (0.61) DPP4F2ADRA2AADRA2CLMNA
SCHEMBL11480062 0.81 DPP4 (0.61) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL1764753 0.81 DPP4 (0.61) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL8518249 0.81 DPP4 (0.61) DPP4F2ADRA2AADRA2CLMNA
Aminodiphenylmethane SCHEMBL6970159 0.81 DPP4 (0.61) DPP4F2ADRA2AADRA2CLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4481373-A CATALYTIC OXIDATION OF OLEFINS IN PRESENCE OF TERTIARY AMINE OF AMIDE TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1984-11-06 US disclosed