Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | FPR2 | P25090 | 1/20 | 0.30 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3238364 | 0.78 | HDAC6 (0.41) | APLNRNR1I2HDAC6MAPK1 | |
| SCHEMBL346024 | 0.78 | HDAC6 (0.41) | APLNRNR1I2HDAC6MAPK1 | |
| SCHEMBL4023097 | 0.75 | APLNR (0.35) | APLNRNR1I2 | |
| SCHEMBL4030776 | 0.73 | APLNR (0.34) | APLNRNR1I2 | |
| SCHEMBL29457012 | 0.73 | APLNR (0.54) | APLNRNR1I2HDAC6FFAR2MAPK1 | |
| SCHEMBL24707419 | 0.72 | APLNR (0.33) | APLNRHDAC6MAPK1 | |
| SCHEMBL3946528 | 0.72 | APLNR (0.34) | APLNRHDAC6 | |
| SCHEMBL3941882 | 0.71 | CNR1 (0.34) | APLNR | |
| SCHEMBL4196483 | 0.70 | CXCR1 (0.35) | APLNRNR1I2 | |
| SCHEMBL4324172 | 0.70 | APLNR (0.35) | APLNRNR1I2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009095712-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | WO | disclosed |