Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL314481 | 0.81 | KMT2A (0.39) | MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL3792048 | 0.80 | P2RY1 (0.46) | KDM4EALDH1A1KMT2AP2RY1 | |
| SCHEMBL316115 | 0.79 | LTA4H (0.42) | MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL8122786 | 0.73 | LMNA (0.50) | MAP4K4ALDH1A1 | |
| SCHEMBL7938427 | 0.72 | MAPT (0.46) | MAP4K4MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL217907 | 0.71 | RAB9A (0.42) | MAPTKDM4EALDH1A1KMT2A | |
| SCHEMBL1031471 | 0.71 | KMT2A (0.44) | MAPTKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18984715 | 0.71 | MAP4K4 (0.50) | MAP4K4MRGPRX1MAPTKDM4EALDH1A1 | |
| SCHEMBL9900619 | 0.71 | MEN1 (0.56) | MAPTALDH1A1HPGDKMT2A | |
| SCHEMBL8128538 | 0.71 | MAPT (0.38) | MAPTKDM4EALDH1A1KMT2ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098517-B1 | NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE | MSD KK (JP) | 2013-12-18 | — | — | EP | disclosed |
| EP-2098517-A1 | NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-09-09 | — | — | EP | disclosed |