SCHEMBL2816581

SCHEMBL2816581

CCOC(C)(C)c1ccc(C(C)(C)OCC)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.40
ALDH1A1 P00352 1/20 0.37
ALOX15 P16050 1/20 0.37
NQO1 P15559 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
ESR1 P03372 4/20 0.32
ESR2 Q92731 4/20 0.32
TSHR P16473 2/20 0.32
LMNA P02545 1/20 0.31
TYR P14679 1/20 0.31
CYP3A4 P08684 1/20 0.31
AR P10275 1/20 0.31
HPGD P15428 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
HTR6 P50406 1/20 0.31
ESRRG P62508 1/20 0.31
SLC6A3 Q01959 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19144067 0.93 ESR1 (0.42) MAPK1ALDH1A1ALOX15MAPTESR1
SCHEMBL10534242 0.91 TSHR (0.48) MAPK1ALDH1A1ALOX15NPC1MAPT
SCHEMBL18905523 0.89 MAPK1 (0.33) MAPK1ALDH1A1ALOX15
SCHEMBL18156893 0.89 MAPT (0.48) MAPK1ALDH1A1NPC1MAPTRAB9A
SCHEMBL16451453 0.89 APP (0.42) MAPK1ALDH1A1ALOX15NPC1MAPT
SCHEMBL4573159 0.89 CYP2A6 (0.35) MAPK1ALDH1A1ALOX15NPC1MAPT
SCHEMBL43427 0.87 MAPK1 (0.58) MAPK1ALDH1A1ALOX15MAPTESR1
SCHEMBL12139934 0.85 TSHR (0.43) MAPK1ALDH1A1NPC1MAPTRAB9A
SCHEMBL10533573 0.85 ALDH1A1 (0.44) ALDH1A1MAPTLMNATYRHPGD
SCHEMBL19719422 0.85 SHBG (0.53) MAPK1ALDH1A1NPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10544238-B2 Methods of preparing functionalized polyolefins CHEVRON ORONITE COMPANY LLC (US) 2020-01-28 US disclosed
EP-2925804-B1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES CHEVRON ORONITE CO (US) 2019-02-20 EP disclosed
EP-2414432-B1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE CO (US) 2017-05-31 EP disclosed
US-20170096502-A1 METHODS OF PREPARING FUNCTIONALIZED POLYOLEFINS THE UNIVERSITY OF SOUTHERN MISSISSIPPI 2017-04-06 US disclosed
US-9315595-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-04-19 US disclosed
US-9243203-B2 Copolymers of polyaminopolyolefins and polyanhydrides and methods of their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-01-26 US disclosed
US-20140155308-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES AND METHODS OF THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2014-06-05 US disclosed
US-20140031497-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2014-01-30 US disclosed
US-8552122-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-10-08 US disclosed
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-09-30 US disclosed
EP-0415790-B1 Naphthol-based epoxy resins, process for preparing the same, and epoxy resin compositions containing the same NIPPON STEEL CHEMICAL CO (JP) 1999-04-14 EP disclosed
US-5223602-A Impact strength, water resistance NIPPON STEEL CHEMICAL CO., LTD. (JP) 1993-06-29 US disclosed
US-5068293-A Heat resistant and moisture resistant epoxy resin for molding materials NIPPON STEEL CHEMICAL CO., LTD. (JP) 1991-11-26 US disclosed
EP-0415790-A2 Naphthol-based epoxy resins, intermediates for the same, process for preparing the same, and epoxy resin compositions containing the same NIPPON STEEL CHEMICAL CO., LTD. (JP) 1991-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION TERT, TELO2, TSPO MAPK1 3832/4885ALDH1A1 3744/4885ALOX15 1483/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.