Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 11/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713124 | 0.78 | NFE2L2 (0.56) | NFE2L2TRPA1RELAGRIN2DGRIN3B | |
| SCHEMBL434482 | 0.76 | NFE2L2 (0.44) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL9045807 | 0.73 | GABRA1 (0.45) | — | |
| SCHEMBL5833284 | 0.73 | GABRA1 (0.35) | MAPT | |
| SCHEMBL23457275 | 0.73 | NFE2L2 (0.56) | NFE2L2GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL4890473 | 0.72 | NFE2L2 (0.50) | NFE2L2TRPA1RELAGRIN2DGRIN3B | |
| SCHEMBL4817482 | 0.72 | SMPD2 (0.43) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL3712847 | 0.71 | NFE2L2 (0.54) | NFE2L2RELAGRIN2DGRIN3BGRIN1 | |
| SCHEMBL1759710 | 0.71 | NFE2L2 (0.54) | NFE2L2TRPA1GRIN2DGRIN3BGRIN1 | |
| SCHEMBL4196373 | 0.71 | NFE2L2 (0.48) | NFE2L2TRPA1RELAGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |