Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031672 | 0.91 | TDP1 (0.54) | ESR1ESR2TDP1MAPTL3MBTL1 | |
| SCHEMBL10624763 | 0.90 | ESR1 (0.55) | ESR1ESR2TDP1MAPTL3MBTL1 | |
| SCHEMBL8905305 | 0.89 | MAPT (0.50) | ESR1ESR2TDP1MAPTL3MBTL1 | |
| SCHEMBL4346502 | 0.89 | MAPT (0.50) | ESR1ESR2TDP1MAPTL3MBTL1 | |
| SCHEMBL14287528 | 0.85 | ESR1 (0.50) | ESR1ESR2TDP1MAPTL3MBTL1 | |
| SCHEMBL10032079 | 0.84 | ESR1 (0.49) | ESR1ESR2TDP1MAPTKDM4E | |
| SCHEMBL20717654 | 0.84 | ESR1 (0.62) | ESR1ESR2KDM4EPOLBALDH1A1 | |
| SCHEMBL24385840 | 0.84 | MAPT (0.59) | TDP1MAPTL3MBTL1KDM4EPOLB | |
| SCHEMBL13526085 | 0.83 | CYP3A4 (0.57) | ESR1ESR2TDP1MAPTKDM4E | |
| SCHEMBL2335333 | 0.82 | ELANE (0.59) | ESR1ESR2TDP1MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281291-A1 | IMAGING MEMBERS | XEROX CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
| US-20060286469-A1 | Imaging members | XEROX CORPORATION | 2006-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060286469-A1 | Imaging members | VCL, MAP1LC3C, MAP1LC3B | ESR1 2083/4885ESR2 2138/4885TDP1 3816/4885 |
| US-20090281291-A1 | IMAGING MEMBERS | VCL, MAP1LC3C, MAP1LC3B | ESR1 2083/4885ESR2 2138/4885TDP1 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.