Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ESRRG | P62508 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8905305 | 1.00 | MAPT (0.50) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL24385840 | 0.94 | MAPT (0.59) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL1031672 | 0.94 | TDP1 (0.54) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL253201 | 0.92 | ESR1 (0.59) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL8862975 | 0.92 | ESR1 (0.59) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL12289276 | 0.92 | LMNA (0.57) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL17248001 | 0.92 | MAPT (0.49) | MAPTTDP1L3MBTL1KDM4ERAB9A | |
| Bicarbonate SCHEMBL2404791 | 0.91 | ESR1 (0.57) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL16405354 | 0.89 | ELANE (0.45) | MAPTTDP1L3MBTL1ELANEKDM4E | |
| SCHEMBL4345285 | 0.89 | ESR1 (0.55) | MAPTTDP1L3MBTL1ELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281291-A1 | IMAGING MEMBERS | XEROX CORPORATION (US) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281291-A1 | IMAGING MEMBERS | VCL, MAP1LC3C, MAP1LC3B | MAPT 88/4885TDP1 3816/4885L3MBTL1 3503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.