Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | MASP2 | O00187 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | CTSV | O60911 | 2/20 | 0.38 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSK | P43235 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4345868 | 1.00 | PNMT (0.50) | PNMTRIPK1CTSLDPP4TSHR | |
| SCHEMBL4349071 | 0.86 | MEN1 (0.41) | CTSLKIF11ANPEPENPEPCTBP2 | |
| SCHEMBL4349075 | 0.86 | MEN1 (0.41) | CTSLKIF11ANPEPENPEPCTBP2 | |
| SCHEMBL1527219 | 0.85 | EPHX1 (0.48) | PKMANPEPMEN1KMT2ASLC7A5 | |
| SCHEMBL14860145 | 0.85 | EPHX1 (0.48) | PKMANPEPMEN1KMT2ASLC7A5 | |
| SCHEMBL14860143 | 0.85 | EPHX1 (0.48) | PKMANPEPMEN1KMT2ASLC7A5 | |
| SCHEMBL4352830 | 0.85 | SLC1A1 (0.51) | RIPK1DPP4ANPEPENPEPCTSS | |
| SCHEMBL4352828 | 0.85 | SLC1A1 (0.51) | RIPK1DPP4ANPEPENPEPCTSS | |
| SCHEMBL4359730 | 0.84 | SLC6A4 (0.50) | DPP4ANPEPENPEPHTT | |
| SCHEMBL4359724 | 0.84 | SLC6A4 (0.50) | DPP4ANPEPENPEPHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |