Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A1 | P43005 | 2/20 | 0.51 |
| ▸ | DPP4 | P27487 | 5/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.40 |
| ▸ | FAP | Q12884 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4352830 | 1.00 | SLC1A1 (0.51) | SLC1A1DPP4DPP7RIPK1MEN1 | |
| SCHEMBL4349071 | 0.86 | MEN1 (0.41) | MEN1KMT2AANPEPENPEPSLC7A5 | |
| SCHEMBL4349075 | 0.86 | MEN1 (0.41) | MEN1KMT2AANPEPENPEPSLC7A5 | |
| SCHEMBL4349090 | 0.85 | HTR2A (0.55) | DPP4DPP7MEN1KMT2APPARG | |
| SCHEMBL4349086 | 0.85 | HTR2A (0.55) | DPP4DPP7MEN1KMT2APPARG | |
| SCHEMBL1527219 | 0.85 | EPHX1 (0.48) | SLC1A1MEN1KMT2AANPEPSLC7A5 | |
| SCHEMBL14860143 | 0.85 | EPHX1 (0.48) | SLC1A1MEN1KMT2AANPEPSLC7A5 | |
| SCHEMBL14860145 | 0.85 | EPHX1 (0.48) | SLC1A1MEN1KMT2AANPEPSLC7A5 | |
| SCHEMBL4345868 | 0.85 | PNMT (0.50) | DPP4RIPK1MEN1KMT2ACTSS | |
| SCHEMBL4345865 | 0.85 | PNMT (0.50) | DPP4RIPK1MEN1KMT2ACTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |