Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ANPEP | P15144 | 3/20 | 0.41 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349071 | 1.00 | MEN1 (0.41) | MEN1KMT2AANPEPENPEPLMNA | |
| SCHEMBL14860145 | 0.86 | EPHX1 (0.48) | MEN1KMT2AANPEPLMNASLC7A5 | |
| SCHEMBL14860143 | 0.86 | EPHX1 (0.48) | MEN1KMT2AANPEPLMNASLC7A5 | |
| SCHEMBL1527219 | 0.86 | EPHX1 (0.48) | MEN1KMT2AANPEPLMNASLC7A5 | |
| SCHEMBL4352830 | 0.86 | SLC1A1 (0.51) | MEN1KMT2AANPEPENPEPSLC7A5 | |
| SCHEMBL4352828 | 0.86 | SLC1A1 (0.51) | MEN1KMT2AANPEPENPEPSLC7A5 | |
| SCHEMBL4345865 | 0.86 | PNMT (0.50) | MEN1KMT2AANPEPENPEPSLC7A5 | |
| SCHEMBL4345868 | 0.86 | PNMT (0.50) | MEN1KMT2AANPEPENPEPSLC7A5 | |
| SCHEMBL4349086 | 0.84 | HTR2A (0.55) | MEN1KMT2ALMNA | |
| SCHEMBL4349090 | 0.84 | HTR2A (0.55) | MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2070928-A1 | 7-azaindol-3-ylacrylamides active as kinase inhibitors | NERVIANO MEDICAL SCIENCES S.r.l. (IT) | 2009-06-17 | — | — | EP | disclosed |