Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725973 | 0.76 | ALDH1A1 (0.33) | ALDH1A1KDM4EHPGDALDH1A2ALDH2 | |
| SCHEMBL10843557 | 0.76 | TYMP (0.41) | ALDH1A1PGAM1KDM4EHPGDALDH1A2 | |
| SCHEMBL4311567 | 0.71 | ALDH1A1 (0.34) | ALDH1A1KDM4EHPGD | |
| SCHEMBL4305345 | 0.70 | — | — | |
| SCHEMBL16020517 | 0.68 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL31329426 | 0.68 | ALDH1A1 (0.33) | ALDH1A1TYMP | |
| SCHEMBL31329417 | 0.67 | CTRC (0.35) | ALDH1A1KDM4EHPGDTYMP | |
| SCHEMBL31329395 | 0.64 | POLB (0.36) | ALDH1A1 | |
| SCHEMBL712681 | 0.64 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL12432421 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7611696-B2 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DSM IP ASSETS B.V. (NL) | 2009-11-03 | — | — | US | disclosed |
| EP-1474098-B1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS BV (NL) | 2006-08-02 | — | — | EP | disclosed |
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | ROCHE VITAMINS AG (CH) | 2005-01-27 | — | — | US | disclosed |
| EP-1474098-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP Assets B.V. (NL) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003068183-A1 | SUNSCREEN COMPOSITIONS AS WELL AS DIHYDROPYRIDINES AND DIHYDROPYRANES | DSM IP ASSETS B.V. (NL) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050019278-A1 | Sunscreen compositions as well as dihydropyridines and dihydropyranes | DHPS, DSG1, DHODH | ALDH1A1 154/4885PGAM1 598/4885KDM4E 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.